Original Article
Original Article
/ VOLUME 5, ISSUE 2, JUNE 2023
Özge Kaya and others
Psoriasis, a chronic inflammatory disease, has a multifactorial etiology, including genetic, environmental, and behavioral factors. Since psoriasis is an immune system-mediated disease, immunosuppressive agents and biological treatments are frequently used in its treatment; however, these agents are known to increase the risk of infection. This situation (...) Read More
Original Article
/ VOLUME 5, ISSUE 2, JUNE 2023
Yeşim Yıldız and others
Vaccines to prevent SARS-CoV-2 infection are the most promising and effective approach to curb the COVID-19 pandemic, as well as to reduce hospitalizations and prevent mortality. In our country, the CoronaVac (Sinovac Biotech, China) vaccine started to be administered as of January 13, 2021, and the Comirnaty (BNT162b2, Pfizer-BioNTech) vaccine as (...) Read More
Original Article
/ VOLUME 5, ISSUE 2, JUNE 2023
Reza Kamali Kakhki* and others
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory disease agent belonging to the Betacoronavirus genera. The genome of the virus translates into four major structural proteins, including spike (S), nucleocapsid (N), membrane (M), and envelop (E) proteins. During the pandemic, huge numbers of mutations (...) Read More
Original Article
/ VOLUME 5, ISSUE 2, JUNE 2023
Mustafa Güldan and others
The coronavirus disease 2019 (COVID-19) caused more than 6 million deaths worldwide, and vaccination remains to be the most effective way to reduce the deaths in addition to infection control measures in the community. The Turkish Ministry of Health offered two types of vaccines (...) Read More
Original Article
/ VOLUME 5, ISSUE 2, JUNE 2023
Uluhan Sili* and others
The first coronavirus disease 2019 (COVID-19) case in Turkey was reported on March 11, 2020. The number of confirmed cases with symptoms increased afterward, reaching 5000 per day by mid-April. With the effect of mitigation measures, the number of daily cases started to decline, (...) Read More
Original Article
/ VOLUME 5, ISSUE 3, SEPTEMBER 2023
Yusuf Emre Özdemir and others
Burkholderia cepacia complex is aerobic, non-fermentative, multi-drug resistant Gram-negative bacilli containing 24 opportunistic pathogenic species (1). B. cepacia complex members are commonly found in natural environments because they easily adapt to harsh environments due to their genotypic and phenotypic plasticity and ability to mutate rapidly. B. cepacia complex can also grow substantially and survive in water-based (...) Read More
Original Article
/ VOLUME 5, ISSUE 3, SEPTEMBER 2023
Hüseyin Bilgin and others
Hospital-acquired respiratory viral infections are associated with increased mortality and morbidity and prolonged hospital stays (1). Hospital-acquired influenza (HAI) accounts for 10-15% of these infections (2-4). Previous studies reported the proportion of HAI to influenza-diagnosed patients admitted to the hospital between 4%-25% (5-8). A systematic review showed that the average proportion of HAI among all hospitalized (...) Read More
Original Article
/ VOLUME 5, ISSUE 3, SEPTEMBER 2023
Sevil Alkan and Esra Gürbüz
Middle East Respiratory Syndrome (MERS) is a viral respiratory infection caused by the MERS coronavirus (MERS-CoV) from the Coronaviridae family. MERS coronavirus was first identified as the etiologic agent from a patient living in Saudi Arabia in 2012, and it is the sixth human coronavirus . After the first case, the infection was detected in Bahrain, Iran, Jordan, Kuwait, Lebanon, Oman, Qatar, Saudi Arabia, the United Arab Emirates, and Yemen. So far, all MERS-CoV cases worldwide have been associated with a travel history (...) Read More
Original Article
/ VOLUME 5, ISSUE 3, SEPTEMBER 2023
Nuriye Yalçın-Çolak and others
COVID-19, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is a zoonotic infection that emerged in Wuhan province of China in December 2019. SARS-COV-2 is a Betacoronavirus that is classified in Riboviria realm, Nidovirales order, and Coronaviridae family (1). Although the fatality rate of SARS-CoV-2 (2.6%) is lower than SARS-CoV (11%) and MERS-CoV (35-50%), it was much more severe worldwide (...) Read More
Original Article
/ VOLUME 5, ISSUE 3, SEPTEMBER 2023
Elif Mukime Sarıcaoğlu and others
The coronavirus disease 2019 (COVID-19) pandemic, with the increasing number of cases, has been a major health challenge worldwide. In addition to being a significant cause of morbidity and mortality, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection maintains its importance because of prolonged symptoms after acute disease in the post-infectious period. Read More
Original Article
/ VOLUME 5, ISSUE 3, SEPTEMBER 2023
Semiha Solak-Grassie and others
The development of a vaccine was a big step in the fight against COVID-19. However, with the introduction of vaccines in a short time, there were many people in society and among healthcare workers (HCWs) who did not want to get vaccinated. Read More
Original Article
/ VOLUME 5, ISSUE 4, DECEMBER 2023
Emrah Emiral and others
After the declaration of the pandemic on March 11, 2020, by the World Health Organization (WHO), approximately 771 million people were affected by COVID-19 globally, and about 7 million deaths have occurred as of the third week of November 2023. In Turkey, the first COVID-19 case was identified on March 11, 2020 (...) Read More
Original Article
/ VOLUME 5, ISSUE 4, DECEMBER 2023
Hatun Öztürk-Çerik and others
Brucellosis is a widespread zoonosis transmitted to humans, mainly through direct or indirect contact with infected animals. The main endemic areas are the Mediterranean region, Middle East, Central Asia, China, India, sub-Saharan Africa, and Central and South America. Brucellosis is a systemic infection with a broad clinical spectrum (...) Read More
Original Article
/ VOLUME 5, ISSUE 4, DECEMBER 2023
Yağmur Eylül Doğantürk and others
Human adenovirus (HAdV) is a non-enveloped, double-stranded DNA virus that causes self-limiting respiratory system infections, gastrointestinal tract infections, conjunctivitis, and meningitis. These infections are generally observed throughout the year with no seasonal distribution. Despite being self-limiting, HAdV infections (...) Read More
Original Article
/ VOLUME 5, ISSUE 4, DECEMBER 2023
Nilden Dayan and others
Posaconazole is a systemic extended-spectrum triazole mainly licensed for prophylaxis of invasive fungal infections (IFIs) in high-risk patients. Three formulations of posaconazole are currently available, including an oral suspension (40 mg/mL), a delayed-release gastric-resistant (...) Read More
Original Article
/ VOLUME 5, ISSUE 4, DECEMBER 2023
Deniz Gür-Altunay and Pınar Yürük-Atasoy
Hepatitis B virus (HBV) infection is an important public health problem worldwide. It is the most important cause of acute and chronic liver disease and hepatocellular cancer. Hepatitis B infection is diagnosed by the detection of HBsAg in the serum or plasma. Chronic hepatitis B (CHB) infection is defined as the persistence of (...) Read More
Original Article
/ VOLUME 5, ISSUE 4, DECEMBER 2023
Özge Özgen-Top and others
Influenza-like illness (ILI) can be caused by a range of respiratory viruses in adults. Influenza is one of the most important respiratory viruses that affects all age groups and can lead to hospitalizations. Severe influenza and complications can cause significant morbidity and mortality during pandemics, epidemics, and sporadic outbreaks. Therefore, influenza (...) Read More
Original Article
/ VOLUME 5, ISSUE 4, DECEMBER 2023
Işıl Deniz Alıravcı and others
Human metapneumovirus (hMPV) is an enveloped, single-stranded ribonucleic acid (RNA) virus in the genus Metapneumovirus. In 2016, the Pneumoviridae family replaced Paramyxoviridae as a new classification for this virus. Read More
Original Article
/ VOLUME 5, ISSUE 4, DECEMBER 2023
Oğuz Evlice and others
Acute lung injury and sepsis are among the severe clinical outcomes of the coronavirus disease 2019 (COVID-19). Risk factors raise fatality rates, increase the burden on countries’ healthcare facilities, and significantly increase health expenditures due to prolonged inpatient periods. Several studies have revealed a severe illness course in COVID-19 patients, especially in males, older age, and comorbid (...) Read More
Original Article
/ VOLUME 5, ISSUE 4, DECEMBER 2023
Grace Fisler and others
Elevated procalcitonin levels are associated with increased bacterial infection rates in children and adults. Identification of bacterial infection in previous studies has used procalcitonin thresholds of 0.5 ng/mL-1.0 ng/mL. Procalcitonin level elevations have been reported in COVID-19 patients (...) Read More