The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

Original Article

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Original Article / VOLUME 8, ISSUE 5, SEPTEMBER 2026

Eleven-Year Trends in Antimicrobial Resistance and Isolation Rates per 1000 Patient-Days of Key Gram-Positive and Gram-Negative Bacteria in a Tertiary Care Hospital in Türkiye (2014–2024)

Reyhan Balkaya Demirtaş and others

Antimicrobial resistance (AMR) is a critical global health threat, contributing to increased mortality and substantial economic costs. The World Bank has projected an additional USD 1 trillion in healthcare costs by 2050 [...] Read More
Original Article / VOLUME 8, ISSUE 4, JULY 2026

Efficacy and Cost Analysis of a Combined (One-Step) Detergent-Disinfectant for Environmental Decontamination Around Methicillin-Resistant Staphylococcus aureus (MRSA) Patients

Leo Lui and others

Multidrug-resistant organisms (MDROs) are common causes of healthcare-associated infections (HAIs), which result in adverse patient outcomes, substantial morbidity and mortality, and increased healthcare-related costs. A growing body of literature [...] Read More
Original Article / VOLUME 8, ISSUE 4, JULY 2026

Epidemiological and Laboratory Evaluation of Central Nervous System Infections Using the BioFire FilmArray Meningitis/Encephalitis Panel in a Tertiary Care Hospital in İstanbul

Serpil S. Çuğlan and others

Acute bacterial meningitis (ABM) is a rapidly progressive disease with outbreak potential and remains associated with substantial morbidity and mortality worldwide. Although vaccination programs have significantly reduced the incidence of several major pathogens, ABM [...] Read More
Original Article / VOLUME 8, ISSUE 3, MAY 2026

Diagnostic Performance of Combination Disk and CIM Tests for Carbapenemase Detection in Enterobacterales Compared with Real-Time Multiplex PCR

Aslı Çabuk and others

Enterobacterales are among the most important causative agents of both community-acquired and hospital-acquired infections. They are major causes of urinary tract infections and bloodstream infections, which are associated with significant morbidity and mortality. In particular, the development of carbapenem resistance [...] Read More
Original Article / VOLUME 8, ISSUE 3, MAY 2026

Upregulation of Serum microRNA-21 as a Noninvasive Biomarker in Active Pulmonary Tuberculosis Patients in Duhok, Iraq

Nishteman Faysal Mohammad and Amir Hani Raziq

Tuberculosis (TB) remains one of the most serious infectious diseases worldwide and continues to represent a major public health challenge, particularly in low- and middle-income countries. According to the World Health Organization (WHO), approximately 10.6 million people developed TB globally in 2022, with an estimated 1.3 million deaths, making TB one of the leading causes [...] Read More
Original Article / VOLUME 8, ISSUE 2, MARCH 2026

Modification of CLSI Recommended Colistin Agar Test for Enterobacterales to Handle Large Sample Load in a High-Throughput Laboratory

Prabhav Aggarwal and others

The uncontrolled and unmonitored overuse of antimicrobials in healthcare, agriculture, and animal husbandry has led to a global health crisis, resulting in resistance to both commonly used and reserve antibiotics. Gram-negative bacteria have developed resistance to higher-tier agents, posing [...] Read More