The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)
Childhood vaccination is a cornerstone of public health, substantially reducing morbidity and mortality from vaccine-preventable infectious diseases. Nevertheless, vaccine hesitancy and refusal have emerged as growing global challenges (...) Read More
Respiratory tract infections (RTIs) are a leading cause of morbidity and mortality worldwide, particularly among vulnerable populations such as young children, older adults, and immunocompromised individuals. Read More
Natural disasters are catastrophic events that occur as part of the natural ecological system and may result in fatalities, traumatic injuries, secondary morbidity, and substantial economic losses. Among natural disasters causing human (...) Read More
Mucormycosis is a fungal infection caused by members of the order Mucorales, including Rhizopus, Mucor, Rhizomucor, Actinomucor, Apophysomyces, Cunninghamella, Lichtheimia, Saksenaea, and Syncephalastrum (...) Read More
Brucella melitensis is the most common causative agent of human brucellosis worldwide and in Türkiye (1,2). Genomic evidence obtained from an approximately 8000-year-old sheep specimen in Menteşe Höyük in northwestern Türkiye (...) Read More
Salmonella infections are among the most common infectious diseases worldwide, with an estimated 550 million cases annually, particularly affecting children under five years of age (1). Although these infections are often mild (...) Read More
Infections caused by carbapenem-resistant Gram-negative bacteria have become a significant global public health problem due to the growing burden of antimicrobial resistance. According to predictive analyses, approximately 4.95 million (...) Read More
Aerobic, non-spore-forming, Gram-positive bacilli of the Corynebacterium genus are frequently regarded as contaminants when isolated from blood cultures, as they are part of the normal skin and mucosal flora. Among these, Corynebacterium striatum, a coryneform bacterium commonly isolated in clinical microbiology laboratories, has recently been identified as a potential pathogen in both (...) Read More
Bloodstream infections remain a common and life-threatening complication among patients with hematological malignancies. These individuals are prone to bacteremia due to cytotoxic chemotherapy, prolonged and severe neutropenia, and mucosal barrier injury (...) Read More
Chikungunya fever, caused by chikungunya virus, is characterized by acute high-grade fever, rash, myalgia, joint pain, and polyarthralgia. Although its symptoms resemble those of dengue infection, the two diseases differ in prognosis and clinical manifestation. Chikungunya fever is typically self-limiting, lasting for 2–6 days; however, joint pain may persist for more than two years (...) Read More
Mpox, previously known as monkeypox, is a rare zoonotic infectious disease caused by the monkeypox virus (MPXV), an enveloped DNA virus belonging to the Orthopoxvirus genus of the Poxviridae family. MPXV is closely (...) Read More
Despite revolutionary advances in antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection remains a global public health issue. Effective ART regimens have transformed the infection from a fatal disease into a manageable chronic condition, significantly reducing AIDS-related opportunistic infections (...) Read More
Respiratory tract infections are among the most common causes of hospitalizations worldwide. An important part of respiratory tract infections is caused by viral pathogens. Respiratory viruses are associated with 22% to 26.2% of community-acquired pneumonia. However, clinical signs and symptoms, physical examination, routine laboratory tests, and routine microbiological (...) Read More
Multidrug-resistant Gram-negative bacteria cause infections that are difficult to treat and associated with high mortality rates. Such infections are a major problem in Türkiye and worldwide. The carbapenem group of antibiotics is commonly used in infections caused by resistant Gram-negative microorganisms. However, the frequent use of carbapenems has caused more serious issues, including (...) Read More
Patient care strategies in modern medicine have become increasingly complex. Global population aging, the expanding use of immunosuppressive therapy, and the rise in invasive procedures have further underscored the pivotal role of infectious diseases specialists in clinical (...) Read More
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, has had a profound global impact, infecting approximately 800 million people and causing more than 7 million deaths. In infected individuals, the immune system plays a central role in (...) Read More
Measles is a highly contagious, airborne, acute febrile disease caused by an enveloped, single-stranded RNA virus belonging to the Morbillivirus genus of the Paramyxoviridae family. It typically presents [...] Read More
Immunosuppressive drugs are increasingly used in the treatment of rheumatologic diseases to achieve disease remission, reduce the frequency of attacks, and prevent relapses. Since the late 1990s, advancements in molecular biology, immunology, and pharmaceutical technologies have led to various new treatment approaches for autoimmune-associated inflammatory diseases. Read More
Colistin is an effective drug against aerobic Gram-negative organisms, which are often the primary cause of potentially fatal infections. These pathogens include Klebsiella pneumonia, Escherichia coli, and other Enterobacteriaceae, as well as carbapenem-resistant [...] Read More
Healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) represent major threats to global health. The global increase in AMR is primarily attributed to unnecessary or inappropriate use of antibiotics in humans and animals. Antibiotics, unlike other drugs, are a valuable resource that requires [...] Read More