The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

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Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Detrimental Effects of Sterilization Types on Single-Use Coronary Angioplasty Catheters for Reuse: An Electron Microscopic Study

Tuba Kuruoğlu and others

Reprocessing a disposable medical device in which sterility deteriorates without contact with the blood and body fluids is called “reprocessing.” If it is ready for use by being processed again for the same or another patient, it is named reuse. The increasing number of blood-borne diseases led to the broader use of disposable instruments. Cardiac catheters, (...) Read More

Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Knowledge and Attitudes of Patients About the Rational Use of Antibiotics

Pınar Korkmaz and others

Antimicrobial resistance can lead to morbidity and mortality in serious infections. Therefore, antimicrobial resistance has been accepted as a global public health problem in the 21st century. Unnecessary and excessive use of drugs is a serious problem in our country as well as in the rest of the world. Unnecessarily used drugs play an important role (...) Read More

Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Predictors of Significant Histological Hepatic Abnormality in Treatment-Naive Patients Infected with HBeAg-Negative Chronic Hepatitis B

Gülşah Tunçer and others

Chronic hepatitis B (CHB)  infection is a global health problem that the World Health Organization (WHO) reported 296 million individuals diagnosed with CHB, and 820,000 died worldwide in 2019. In our country, as per the Türkiye Viral Hepatitis Prevention and Control Program for 2018-2023, there have been 3.3 million patients with CHB infection in Türkiye. Read More

Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Individualized High Dose Intravenous Anakinra Treatment in Cancer Patients with COVID-19 Associated Cytokine Storm: A Retrospective Controlled Study

Ramazan Çakmak and Murat Bektaş

Coronavirus disease 2019 (COVID-19) is a potentially life-threatening disease caused by SARS-CoV-2. Clinical findings of COVID-19 are ranged from asymptomatic to severe pneumoniae, acute respiratory distress syndrome, multiorgan failure and death. A severe COVID-19 course is associated with a higher inflammatory state (cytokine storm) due to the excessive release (...) Read More

Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Infection Risk Prediction in Healthcare Settings: Lessons from COVID-19 Contact Tracing

Salih Keskin and others

Contact tracing has been recognized as a critical process in controlling infectious disease epidemics. Its objectives include early identification of potentially infectious cases and prevention of the emergence of new clusters. In the context of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, in-hospital contact-tracing efforts (...) Read More

Original Article / VOLUME 6, ISSUE 1, MARCH 2024

How Reliable is ChatGPT as a Novel Consultant in Infectious Diseases and Clinical Microbiology?

Gülşah Tunçer and Kadir Görkem Güçlü

Artificial intelligence models have influenced many branches of science in recent years. It is used in various departments of medicine. ChatGPT (Chat Generative Pre-trained Transformer) is a text-based artificial intelligence model developed by OpenAI. ChatGPT can be used in many areas of medicine, such as to generate medical text, answer medical questions, provide recommendations for diagnosis and treatment (...) Read More

Original Article / VOLUME 5, ISSUE 4, DECEMBER 2023

Association of Serum Krebs von den Lungen-6 (KL-6) Levels and Disease Severity in Patients Hospitalized with COVID-19

Oğuz Evlice and others

Acute lung injury and sepsis are among the severe clinical outcomes of the coronavirus disease 2019 (COVID-19). Risk factors raise fatality rates, increase the burden on countries’ healthcare facilities, and significantly increase health expenditures due to prolonged inpatient periods. Several studies have revealed a severe illness course in COVID-19 patients, especially in males, older age, and comorbid (...) Read More

Original Article / VOLUME 5, ISSUE 4, DECEMBER 2023

Bibliometric Analysis of Human Metapneumovirus Studies

Işıl Deniz Alıravcı and others

Human metapneumovirus (hMPV) is an enveloped, single-stranded ribonucleic acid (RNA) virus in the genus Metapneumovirus. In 2016, the Pneumoviridae family replaced Paramyxoviridae as a new classification for this virus. Read More

Original Article / VOLUME 5, ISSUE 4, DECEMBER 2023

Evaluation of Hospitalized Patients with Community-Acquired Influenza-Like Illness During Two Influenza Seasons

Özge Özgen-Top and others

Influenza-like illness (ILI) can be caused by a range of respiratory viruses in adults. Influenza is one of the most important respiratory viruses that affects all age groups and can lead to hospitalizations. Severe influenza and complications can cause significant morbidity and mortality during pandemics, epidemics, and sporadic outbreaks. Therefore, influenza (...) Read More

Original Article / VOLUME 5, ISSUE 4, DECEMBER 2023

How Successful Are APRI and FIB-4 Scores in Predicting Liver Fibrosis in Chronic Hepatitis B Patients?

Deniz Gür-Altunay and Pınar Yürük-Atasoy

Hepatitis B virus (HBV) infection is an important public health problem worldwide. It is the most important cause of acute and chronic liver disease and hepatocellular cancer. Hepatitis B infection is diagnosed by the detection of HBsAg in the serum or plasma. Chronic hepatitis B (CHB) infection is defined as the persistence of (...) Read More

Original Article / VOLUME 5, ISSUE 4, DECEMBER 2023

Single-Dose Crossover Comparative Bioavailability Study of Two Different Posaconazole 100 mg Gastro-Resistant Tablets Under Fasted and Fed Conditions in Healthy Volunteers

Nilden Dayan and others

Posaconazole is a systemic extended-spectrum triazole mainly licensed for prophylaxis of invasive fungal infections (IFIs) in high-risk patients. Three formulations of posaconazole are currently available, including an oral suspension (40 mg/mL), a delayed-release gastric-resistant (...) Read More

Original Article / VOLUME 5, ISSUE 4, DECEMBER 2023

Development of a Nanoplate-Based Digital PCR Test Method for Quantitative Detection of Human Adenovirus DNA

Yağmur Eylül Doğantürk and others

Human adenovirus (HAdV) is a non-enveloped, double-stranded DNA virus that causes self-limiting respiratory system infections, gastrointestinal tract infections, conjunctivitis, and meningitis. These infections are generally observed throughout the year with no seasonal distribution. Despite being self-limiting, HAdV infections (...) Read More

Original Article / VOLUME 5, ISSUE 4, DECEMBER 2023

Brucellar Epididymo-Orchitis in a Brucellosis Hyperendemic Region in Türkiye

Hatun Öztürk-Çerik and others

Brucellosis is a widespread zoonosis transmitted to humans, mainly through direct or indirect contact with infected animals. The main endemic areas are the Mediterranean region, Middle East, Central Asia, China, India, sub-Saharan Africa, and Central and South America. Brucellosis is a systemic infection with a broad clinical spectrum (...) Read More

Original Article / VOLUME 5, ISSUE 4, DECEMBER 2023

Psychosocial Status of Healthcare Workers During the COVID-19 Pandemic

Emrah Emiral and others

After the declaration of the pandemic on March 11, 2020, by the World Health Organization (WHO), approximately 771 million people were affected by COVID-19 globally, and about 7 million deaths have occurred as of the third week of November 2023. In Turkey, the first COVID-19 case was identified on March 11, 2020 (...) Read More

Original Article / VOLUME 5, ISSUE 3, SEPTEMBER 2023

Dark Side of the COVID-19 Pandemic; ‘Long COVID’

Elif Mukime Sarıcaoğlu and others

The coronavirus disease 2019 (COVID-19) pandemic, with the increasing number of cases, has been a major health challenge worldwide. In addition to being a significant cause of morbidity and mortality, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection maintains its importance because of prolonged symptoms after acute disease in the post-infectious period. Read More

Original Article / VOLUME 5, ISSUE 3, SEPTEMBER 2023

Long-Term Symptoms and Quality of Life in Persons with COVID-19

Nuriye Yalçın-Çolak and others

COVID-19, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is a zoonotic infection that emerged in Wuhan province of China in December 2019. SARS-COV-2 is a Betacoronavirus that is classified in Riboviria realm, Nidovirales order, and Coronaviridae family (1). Although the fatality rate of SARS-CoV-2 (2.6%) is lower than SARS-CoV (11%) and MERS-CoV (35-50%), it was much more severe worldwide (...) Read More

Original Article / VOLUME 5, ISSUE 3, SEPTEMBER 2023

Bibliometric Analysis of the Publications on Middle East Respiratory Syndrome Coronavirus Published Between 2012-2022

Sevil Alkan and Esra Gürbüz

Middle East Respiratory Syndrome (MERS) is a viral respiratory infection caused by the MERS coronavirus (MERS-CoV) from the Coronaviridae family. MERS coronavirus was first identified as the etiologic agent from a patient living in Saudi Arabia in 2012, and it is the sixth human coronavirus . After the first case, the infection was detected in Bahrain, Iran, Jordan, Kuwait, Lebanon, Oman, Qatar, Saudi Arabia, the United Arab Emirates, and Yemen. So far, all MERS-CoV cases worldwide have been associated with a travel history (...) Read More

Original Article / VOLUME 5, ISSUE 3, SEPTEMBER 2023

Comparison of 28-Day Mortality Between Hospital- and Community-Acquired Influenza Patients

Hüseyin Bilgin and others

Hospital-acquired respiratory viral infections are associated with increased mortality and morbidity and prolonged hospital stays (1). Hospital-acquired influenza (HAI) accounts for 10-15% of these infections (2-4). Previous studies reported the proportion of HAI to influenza-diagnosed patients admitted to the hospital between 4%-25% (5-8). A systematic review showed that the average proportion of HAI among all hospitalized (...) Read More