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Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

Maternal Stress and Neonatal Nutrition during the COVID-19 Era

Alara Altıntaş and others

COVID-19 has been the main focus of the world since the beginning of 2020. The virus has infected over 180 million people and caused about 6 million deaths worldwide up to February of 2022. With its rapid spread, the new coronavirus posed enormous economic, environmental, and social challenges together with health threats to the entire (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

The Effect of the Pandemic on Antifungal Use: What Has Changed?

Vildan Avkan-Oğuz and others

Before coronavirus disease 2019 (COVID-19), antimicrobial stewardship (AMS) programs were essential for managing multidrug-resistant Gram-negative bacterial infections. In contrast, antifungal stewardship (AFS) programs were uncommon as a component of AMS. During the COVID-19 pandemic, both AMS and AFS programs have lost (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

Cognitive Assessment of Young Adults Before and After Initiation of Combination Antiretroviral Therapy

Özlem Gül and others

The presence of cognitive disorders in the human immunodeficiency virus (HIV) infected individuals has been known for a long time. A complete neuropsychological evaluation method is a gold standard for diagnosing HIV-related cognitive impairment (HAND). However, such tests require specially trained personnel and specialized centers, and testing takes a long time. Montreal Cognitive (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

Gardnerella vaginalis: Is it an Underestimated Cause of Urinary Symptoms in Males?

Mert Kılıç and others

Gardnerella vaginalis is an anaerobic, gram-negative/variable, small, pleomorphic microorganism. The jury is still out about the clinical significance of G. vaginalis. It is the predominant microorganism in women with vaginosis and also can be isolated from a vaginal secretion of 40-50% of asymptomatic women . On the other hand, male genitourinary tract infections (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

Risk Factors for Mortality in Patients with Stenotrophomonas maltophilia Bloodstream Infections in Immunocompetent Patients

Şirin Menekşe and others

Stenotrophomonas maltophilia is a Gram-negative, non-fermentative aerobic bacterium that infects patients, especially with severe comorbidities such as hematological malignancies. It is commonly found in the environment and hospital settings. The most common clinical presentations are pneumonia and bloodstream infections (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

Novel SARS-CoV-2 Omicron variants in İstanbul; Rapid Preponderance of BA.2 and BA.5

Yeşim Tuyji-Tok and others

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants have been detected since the summer of 2020, and their critical association with viral load, transmissibility, and escape from the innate-vaccine immune response were demonstrated. Another new variant was identified (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

Antibiotic Use among Patients Hospitalized with COVID-19 and Treated in Three Different Clinics

Oğuz Evlice and others

The clinical spectrum of COVID-19 varies, ranging from asymptomatic infection to critical illness. The most commonly used tool for the classification of disease severity is the National Institute of Health (NIH) severity scale, which has four categories: mild, moderate, severe, and critical. Patients with moderate and severe clinical courses are followed up in wards, while those with (...) Read More

Original Article / VOLUME 4, ISSUE 2, JUNE 2022

Factors Associated with Gram-Negative Bacteremia and Mortality in Neutropenic Patients with Hematologic Malignancies in a High-Resistance Setting

Caglayan Merve Ayaz and others

The number of patients with hematological malignancies (HMs) and those undergoing hematopoietic stem cell transplantation (HSCT) has been on rise during the last three decades. Febrile neutropenia (FN) is the most common complication in this specific patient group and requires urgent intervention. Bacteremia […] Read More

Original Article / VOLUME 4, ISSUE 2, JUNE 2022

Necrotizing Fasciitis: Evaluation of 85 Cases and Usage of LRINEC Score

Ebru Oruç and others

Necrotizing fasciitis (NF), one of the necrotizing soft tissue infections, is an infection that primarily involves subcutaneous adipose tissue, which consists of superficial fascia, vascular and neural structures, and involves in deep fascia and progresses with mortality. It may be difficult to differentiate (...) Read More

Original Article / VOLUME 4, ISSUE 2, JUNE 2022

HIV and SARS‐Cov‐2 Co-Infection: A Local Perspective

Heval Can Bilek and Aydın Deveci

In early December 2019, interstitial pneumonia of unknown origin emerged in Wuhan, the capital of China’s Hubei province. The pathogen was identified as a novel beta coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the disease caused by SARS-CoV-2 was later named (...) Read More

Original Article / VOLUME 4, ISSUE 2, JUNE 2022

Appropriate Use of Tocilizumab in COVID-19: Early Use is Beneficial

Lütfiye Nilsun Altunal and others

Clinically COVID-19 can be observed with mild symptoms such as fever, malaise, cough, and also severe symptoms such as acute respiratory distress syndrome (ARDS) that may require respiratory support in up to 25% of the patients . COVID-19 has a high mortality rate, in hospitalized (...) Read More

Original Article / VOLUME 4, ISSUE 2, JUNE 2022

Nasopharyngeal Carriage and Serotype Distribution of Streptococcus pneumoniae in Elderly: A Cross-sectional Study in Turkey

Muammer Çelik and others

Invasive pneumococcal disease (IPD) caused by Streptococcus pneumoniae is an important cause of morbidity and mortality among young children and adults 65 years and older. S. pneumoniae is one of the most important causes of serious diseases, such as pneumonia, meningitis, and bacteremia. According to 2018 surveillance data from US Centers for Disease (...) Read More

Original Article / VOLUME 4, ISSUE 2, JUNE 2022

West Nile Virus Seroprevalence in Manisa Province: A Population-based Study

Abdurrahman Gülmez and others

West Nile Virus (WNV) is an enveloped RNA virus with icosahedral symmetry and with a size of 45-50 nm belonging to the family Flaviviridae, genus Flavivirus (1). The virus, which was first isolated from a woman living in the West Nile region of Uganda in 1937, was noted with consecutive outbreaks in North Africa (...) Read More

Original Article / VOLUME 4, ISSUE 1, MARCH 2022

ANTIBACDUS-PAN: Antibacterial Utilization among Adult Patients Before and During COVID-19 Pandemic within 12-Months Period: A Tertiary Hospital Pharmacoepidemiology Study

Ege Anıl Uçar and others

Rational use of medicines (RUM) has been a concern worldwide for half a century, and is of great importance, given that almost half of all prescribed drugs are irrational. The irrational use of drugs can be disastrous and may cause adverse events, creating a (...) Read More

Original Article / VOLUME 4, ISSUE 1, MARCH 2022

Evaluation of Tenofovir Disoproxil Fumarate Treatment in Patients with Chronic Hepatitis B

Petek Konya and Neşe Demirtürk

Chronic hepatitis B (CHB) is one of the major causes of chronic liver diseases worldwide. Around 296 million people were living with chronic hepatitis B infection in 2019, with 1.5 million new infections each year and more than 820 thousand people losing their life because of hepatitis B virus (HBV) related complications.  Chronic HBV (...) Read More

Original Article / VOLUME 4, ISSUE 1, MARCH 2022

Predictors of Severity and Mortality in COVID-19: A Retrospective Study from Batman, Turkey

Fethiye Akgül and others

At the beginning of the 21st century, three deadly epidemics related to coronaviruses have struck the world. Severe acute respiratory syndrome (SARS) originated in 2002, Middle East respiratory syndrome (MERS) in 2012, and finally COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019. COVID-19 (...) Read More

Original Article / VOLUME 4, ISSUE 1, MARCH 2022

COVID-19 in Elderly Patients: Risk Factors for Disease Severity

Pınar Korkmaz and others

At the end of 2019, a novel coronavirus was identified as the cause of a cluster of pneumonia cases in Wuhan, a city in the Hubei Province of China. It spread rapidly, resulting in a pandemic throughout the world. In February 2020, the World Health Organization (WHO) named the disease COVID-19. Studies reported that COVID-19 mostly progressed with asymptomatic (...) Read More