Original Article
Original Article
/ VOLUME 7, ISSUE 1, MARCH 2025
Bahar Madran and others
Healthcare-associated infections (HAIs) are accepted as one of the most important challenges in hospital settings. They cause extended lengths of stay -at the hospital, threatening patient safety, increasing the rate of morbidity and mortality, raising the workforce of healthcare workers and accelerating antimicrobial resistance. According to the World Health Organization (WHO), [...] Read More
Original Article
/ VOLUME 7, ISSUE 1, MARCH 2025
Fatih Mehmet Akıllı and others
Hepatitis C virus (HCV) is an enveloped, single-stranded, positive polarity RNA virus from the Flaviviridae family. It is part of the Hepacivirus genus, wrapped in a lipid bilayer containing two viral glycoproteins (E1 and E2). HCV infection is a major public health problem that can lead to complications such as cirrhosis and liver cancer. Approximately 85% of people [...] Read More
Original Article
/ VOLUME 7, ISSUE 1, MARCH 2025
Barış Gülhan and others
Rapid diagnosis of pathogens grown in blood cultures reduces mortality and morbidity as appropriate treatment is started early. It notably reduces hospital costs because of less need for intensive care and earlier patient discharge. Although rapid identification and antibiogram of pathogens can be made with automated blood [...] Read More
Original Article
/ VOLUME 7, ISSUE 1, MARCH 2025
Hanife Nur Karakoç-Parlayan and others
The demographic shift with an aging population worldwide has highlighted the unique healthcare challenges the elderly face. According to the Turkish Statistical Institute data, the population aged 65 and over reached 8,722,806 in 2023, accounting for 10.2% of the total population. Population projections indicate that the proportion of the elderly population is expected to reach 12.9% in 2030 [...] Read More
Original Article
/ VOLUME 7, ISSUE 1, MARCH 2025
Pelin İrkören and others
The residency program of infectious diseases and clinical microbiology (IDCM) in Türkiye was started in 1983 by adopting the name IDCM. The IDCM program in Türkiye is a five-year program, including related clinical rotations. Presenting a thesis at the end of this program is mandatory. The first specialty thesis in the field of IDCM was [...] Read More
Original Article
/ VOLUME 7, ISSUE 1, MARCH 2025
Aybegüm Özşahin and others
With the prolongation of life expectancy and the developments in orthopedic surgery, noteworthy progress has been made in prosthetic joint surgery in recent years. Joint replacement provides pain relief, improves quality of life, and gives independence to individuals. Along with the advances in prosthetic surgery, prosthetic joint infection (PJI) is still the most feared complication of the procedure. Read More
Original Article
/ VOLUME 7, ISSUE 1, MARCH 2025
Ebru Yücebağ-Duranay and others
Human pegiviruses (HPgV-1 and HPgV-2) are enveloped, single-stranded positive-sense RNA viruses belonging to the Pegivirus genus in the Flaviviridae family. HPgV has a genome of 8.9-11.3 kb, and the virion size is estimated at around 50-100 nm. Seven genotypes of HPgV-1 differ geographically. Two subtypes of genotype (GT) 2, which is common in Europe [...] Read More
Original Article
/ VOLUME 7, ISSUE 1, MARCH 2025
Yusuf Emre Özdemir and others
Peritonitis presents an inflammation of the peritoneal cavity that can develop because of infectious (bacteria, viruses, parasites, etc.) and non-infectious (chemical agents, foreign substances, etc.) causes. Infectious peritonitis is divided into three classes based on [...] Read More
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
Fatihan Pınarlık and others
COVID-19 is caused by SARS-CoV-2 from the Coronaviridae family, Orthocoronaviridae sub family, Betacoronavirus genus, and Sarbecovirus subfamily (1). Cytokines and chemokines have been essential in the immune response against coronaviruses (2). First reports investigating clinical features of COVID-19 showed that serum levels of interleukin (IL)-2, IL-7, IL-10, granulocyte colony-stimulating factor (GSCF), IP10 (CXCL10), [...] Read More
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
Sinan Çetin and Mediha Uğur
Clostridioides difficile is an anaerobic, Gram-positive, spore-forming bacteria found in the colon as part of the normal intestinal flora of a healthy individual. However, changes in the gut microbiota because of antibiotic use can lead to overgrowth of C. difficile and toxin […] Read More
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
İlker Devrim and others
The most common and serious complication of central venous catheter usage is central line–associated bloodstream infections (CLABSIs) in children and adults. Between 2011 and 2014, CLABSIs were the most frequently reported healthcare-associated illness among hospitals in the USA. Bloodstream infections associated with central lines are […] Read More
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
Melike İnan-Hekimoğlu and others
Cytomegalovirus (CMV) is a DNA virus from the Herpesviridae family that can remain latent in the body for life after primary infection and reactivate and cause viral shedding, especially in cases of immunosuppression. In studies conducted in different patient groups from Türkiye, CMV seroprevalence was reported to be between 85-100%. CMV can affect […] Read More
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
Oruç Numan Gökçe and others
Cystic echinococcosis (CE), caused mainly by Echinococcus granulosus, is a parasitic disease common in Mediterranean countries such as Türkiye. Although it can occur anywhere in the body, it predominantly affects the liver. The disease is often asymptomatic; thus, cysts are often detected incidentally during imaging studies performed for other purposes. Read More
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
Muhammet Çağrı Yıldız and others
Real-time reverse transcriptase polymerase chain reaction (RT-PCR) is widely used to diagnose SARS-CoV-2. However, PCR tests need expensive equipment and qualified personnel, which makes them only used in high throughput and advanced laboratory settings. Improvements in SARS-CoV-2 diagnosis with easy, rapid, and cost-effective approaches […] Read More
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
Khalis Mustafayev and others
Invasive Candida infections have increased significantly in recent years due to various risk factors, including invasive procedures, vascular catheterization, intra-abdominal surgery, prolonged use of broad-spectrum antibiotics, immunosuppressive medications, hemodialysis, total parenteral nutrition (TPN), and extended intensive care unit (ICU) stays. Candida, one of the top three nosocomial bloodstream infections, [...] Read More
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
Dilara Yıldırım and others
Tuberculosis (TB) is a common disease with high mortality and morbidity worldwide. Globally, an estimated 10.6 million people (95% uncertainty interval [UI]=9.9-11.4 million) developed TB in 2022, compared with 10.3 million in 2021 and 10.0 million in 2020. TB caused an estimated 1.30 million deaths worldwide in 2022 (95% UI=1.18-1.43 million). This was […] Read More
Original Article
/ VOLUME 6, ISSUE 3, SEPTEMBER 2024
Süreyya Damar-Örenler and others
Human immunodeficiency virus (HIV) remains a significant global health challenge with societal impacts. Despite a decline in the annual number of new cases worldwide, the incidence of HIV is on the rise in the Eastern Europe/Central Asia region, including Türkiye. With the introduction of new antiretroviral treatments (ARTs), HIV has transitioned from a […] Read More
Original Article
/ VOLUME 6, ISSUE 3, SEPTEMBER 2024
Zeynep Bilgiç and others
The use of antiretroviral therapy (ART) in individuals with the human immunodeficiency virus (HIV) has significantly increased their life expectancy. Nevertheless, an increase in the frequency of chronic diseases such as diabetes mellitus (DM), hypertension (HT), and cardiovascular disease (CVD) in this population with advancing age is expected. Also, they are at greater […] Read More
Original Article
/ VOLUME 6, ISSUE 3, SEPTEMBER 2024
Kauke Bakari Zimbwe and others
Antimicrobial resistance (AMR) is declared one of humanity’s top ten global public health threats. AMR is associated with increased hospitalizations, extended hospital stays, readmissions, and a higher mortality risk. In 2019, 4.95 million deaths, including 1.27 million directly attributable, were associated with bacterial AMR. Sub-Saharan Africa has the highest all-age death rate [...] Read More
Original Article
/ VOLUME 6, ISSUE 3, SEPTEMBER 2024
Kadir Görkem Güçlü and others
Hepatitis B virus (HBV) infection remains a significant public health issue globally. According to the latest data released by the World Health Organization (WHO) in July 2023, the number of individuals living with chronic hepatitis B (CHB) infection as of 2019 was reported as 296 million, with 820 million deaths attributed to cirrhosis and hepatocellular carcinoma [...] Read More