The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

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Original Article / VOLUME 7, ISSUE 4, DECEMBER 2025

Corynebacterium striatum Infective Endocarditis from Different Perspectives: A Comprehensive Literature Review

Elif Mukime Sarıcaoğlu and others

Aerobic, non-spore-forming, Gram-positive bacilli of the Corynebacterium genus are frequently regarded as contaminants when isolated from blood cultures, as they are part of the normal skin and mucosal flora. Among these, Corynebacterium striatum, a coryneform bacterium commonly isolated in clinical microbiology laboratories, has recently been identified as a potential pathogen in both (...) Read More

Original Article / VOLUME 7, ISSUE 4, DECEMBER 2025

Surge of Chikungunya Cases in Central India, Post-COVID-19 Pandemic

Sadhna Sodani and others

Chikungunya fever, caused by chikungunya virus, is characterized by acute high-grade fever, rash, myalgia, joint pain, and polyarthralgia. Although its symptoms resemble those of dengue infection, the two diseases differ in prognosis and clinical manifestation. Chikungunya fever is typically self-limiting, lasting for 2–6 days; however, joint pain may persist for more than two years (...) Read More

Original Article / VOLUME 7, ISSUE 4, DECEMBER 2025

Changing HIV Epidemiology: A Retrospective Analysis of a Single-Center Experience

Yasemin Çakır-Kıymaz and Seyit Ali Büyüktuna

Despite revolutionary advances in antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection remains a global public health issue. Effective ART regimens have transformed the infection from a fatal disease into a manageable chronic condition, significantly reducing AIDS-related opportunistic infections (...) Read More

Original Article / VOLUME 7, ISSUE 4, DECEMBER 2025

Impact of Real-Time Multiplex PCR Testing for Respiratory Viruses on Antibiotic Use

Zeynep Tekin-Taş and others

Respiratory tract infections are among the most common causes of hospitalizations worldwide. An important part of respiratory tract infections is caused by viral pathogens. Respiratory viruses are associated with 22% to 26.2% of community-acquired pneumonia. However, clinical signs and symptoms, physical examination, routine laboratory tests, and routine microbiological (...) Read More

Original Article / VOLUME 7, ISSUE 4, DECEMBER 2025

Ceftazidime-Avibactam: A Retrospective Analysis of Multicenter Real-World Data and Factors Affecting Mortality

Nazlım Aktuğ-Demir and others

Multidrug-resistant Gram-negative bacteria cause infections that are difficult to treat and associated with high mortality rates. Such infections are a major problem in Türkiye and worldwide. The carbapenem group of antibiotics is commonly used in infections caused by resistant Gram-negative microorganisms. However, the frequent use of carbapenems has caused more serious issues, including (...) Read More

Original Article / VOLUME 7, ISSUE 4, DECEMBER 2025

Clinical Roles of Infectious Diseases Specialists in Ophthalmology

Fatma Merve Koçak and Berru Yargı-Özkoçak

Patient care strategies in modern medicine have become increasingly complex. Global population aging, the expanding use of immunosuppressive therapy, and the rise in invasive procedures have further underscored the pivotal role of infectious diseases specialists in clinical (...) Read More

Original Article / VOLUME 7, ISSUE 3, SEPTEMBER 2025

Measles: The Re-emergence of a Vaccine-Preventable Disease

Ahmet Şahin and others

Measles is a highly contagious, airborne, acute febrile disease caused by an enveloped, single-stranded RNA virus belonging to the Morbillivirus genus of the Paramyxoviridae family. It typically presents [...] Read More

Original Article / VOLUME 7, ISSUE 3, SEPTEMBER 2025

Monitoring of Patients Receiving Immunosuppressive and Biological Agent Treatments for Infectious Complications

Ayşe Gülden Bekgöz and others

Immunosuppressive drugs are increasingly used in the treatment of rheumatologic diseases to achieve disease remission, reduce the frequency of attacks, and prevent relapses. Since the late 1990s, advancements in molecular biology, immunology, and pharmaceutical technologies have led to various new treatment approaches for autoimmune-associated inflammatory diseases. Read More

Original Article / VOLUME 7, ISSUE 3, SEPTEMBER 2025

Antimicrobial Use at a Tertiary-Care Hospital in Türkiye According to the WHO Access, Watch and Reserve (AWaRe) Classification: A Point Prevalence Survey

Muammer Çelik and others

Healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) represent major threats to global health. The global increase in AMR is primarily attributed to unnecessary or inappropriate use of antibiotics in humans and animals. Antibiotics, unlike other drugs, are a valuable resource that requires [...] Read More

Original Article / VOLUME 7, ISSUE 3, SEPTEMBER 2025

Impact of the COVID-19 Pandemic on CLABSI Rates and Antibiotic Resistance: A Multicenter Study in Türkiye

Elif Sargın-Altunok and others

Healthcare-associated infections (HAIs) are common yet largely preventable through adherence to evidence-based guidelines. In 2005, Türkiye implemented a national infection control program, which led to significant reductions in HAI rates, including a 50% decrease in central line-associated bloodstream infections (CLABSIs) between 2008 and 2017. This result was in parallel with data from [...] Read More

Original Article / VOLUME 7, ISSUE 3, SEPTEMBER 2025

Clinical Features, Treatment Interventions, and Oral Health-Related Quality of Life in Patients with COVID-19-Associated Mucormycosis: A Descriptive-Analytical Study

Sana Baghban and others

The COVID-19 pandemic has had a profound negative impact on global human health, due to both direct harmful effects of the SARS-CoV-2 virus and the associated superinfections. Notably, two mold infections—aspergillosis and mucormycosis—have been observed in affected patients. Read More

Original Article / VOLUME 7, ISSUE 3, SEPTEMBER 2025

Comprehensive Molecular Epidemiology of HPV in a High-Volume Tertiary Center

İsmail Selçuk Aygar and Mehmet Tevfik Yavuz

Human papillomavirus (HPV) is a non-enveloped, double-stranded DNA virus that infects humans exclusively. It is classified within the Papillomaviridae family and replicates in skin and mucosal epithelial cells. Human papillomavirus is regarded as one of the most prevalent sexually transmitted viral infections, having the capacity [...] Read More

Original Article / VOLUME 7, ISSUE 3, SEPTEMBER 2025

Analyzing Turkish-Language HPV Vaccination Videos on YouTube: Assessing Content Quality and Educational Value

Elif Özeller and others

Cervical cancer is the fourth most common cancer among women worldwide. Epidemiologically and molecularly, the human papillomavirus (HPV) is a circular, double-stranded DNA virus known to cause chronic infections and is the primary cause of cervical cancer. Other cancers associated with HPV include vulvar[...] Read More

Original Article / VOLUME 7, ISSUE 2, JUNE 2025

Characteristics and Distribution of Fungal Meningitis: A Systematic Review

Armina Khalilzadegan and others

In recent decades, fungal infections of the central nervous system (CNS) have increased significantly. Of more than 100,000 identified fungal species, approximately 10 to 15% are responsible for implicated fungal-related neurological diseases. A significant clinical manifestation of fungal infections of the CNS is meningitis, a serious condition marked [...] Read More

Original Article / VOLUME 7, ISSUE 2, JUNE 2025

The Definition, Prevalence, and Risk Factors of Augmented Renal Clearance in Adult Patients on Antimicrobial Therapy: A Scoping Review

Hasan Memiş and others

Antibiotic resistance has become a significant public health concern, primarily due to irrational antibiotic use. Healthcare and antimicrobial stewardship depend on using antibiotics correctly for several reasons. In the first place, adhering to the prescribed dosage ensures that the body receives the right amount of antibiotics to treat [...] Read More