The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)
Immunosuppressive drugs are increasingly used in the treatment of rheumatologic diseases to achieve disease remission, reduce the frequency of attacks, and prevent relapses. Since the late 1990s, advancements in molecular biology, immunology, and pharmaceutical technologies have led to various new treatment approaches for autoimmune-associated inflammatory diseases. Read More
Healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) represent major threats to global health. The global increase in AMR is primarily attributed to unnecessary or inappropriate use of antibiotics in humans and animals. Antibiotics, unlike other drugs, are a valuable resource that requires [...] Read More
Nocardia is a genus of aerobic, Gram-positive bacteria found in soil, decomposing organic matter, and water. It primarily causes infections in individuals with compromised immune systems. Pulmonary infections represent the most frequent manifestation of Nocardia-associated diseases, while extrapulmonary spread often involves [...] Read More
Historically, Mycoplasma hominis was the first mycoplasma species isolated from humans, first identified in 1937 from a Bartholin’s gland abscess. It is a small, coccoid-shaped (approximately 0.5 μm), Gram-negative bacterium that grows slowly in culture. Due to the lack of a cell wall, M. hominis is resistant to beta-lactam antibiotics. Read More
Colistin is an effective drug against aerobic Gram-negative organisms, which are often the primary cause of potentially fatal infections. These pathogens include Klebsiella pneumonia, Escherichia coli, and other Enterobacteriaceae, as well as carbapenem-resistant [...] Read More
The COVID-19 pandemic has had a profound negative impact on global human health, due to both direct harmful effects of the SARS-CoV-2 virus and the associated superinfections. Notably, two mold infections—aspergillosis and mucormycosis—have been observed in affected patients. Read More
Human papillomavirus (HPV) is a non-enveloped, double-stranded DNA virus that infects humans exclusively. It is classified within the Papillomaviridae family and replicates in skin and mucosal epithelial cells. Human papillomavirus is regarded as one of the most prevalent sexually transmitted viral infections, having the capacity [...] Read More
Crimean-Congo hemorrhagic fever (CCHF) is a disease that causes serious morbidity and mortality and can affect multiple organ systems. The Crimean-Congo hemorrhagic fever virus (CCHFV) belongs to the Nairoviridae family within the order Bunyavirales, which comprises enveloped, negatively [...] Read More
It is with deep sorrow that we announce the passing of Professor Emel Tümbay on August 6, 2025, at the age of 84. She was a distinguished pioneer in Medical Mycology. Professor Tümbay was held in the highest esteem by the international scientific community and her colleagues at Ege University’s Faculty of Medicine in Türkiye. Read More
The Portable Bath was designed by Santorio Santori (1561–1636), known as the father of quantified medicine and experimental physiology, in 1610. Without getting out of bed, the patient wears a leather suit that is (...) Read More
Measles is a highly contagious, airborne, acute febrile disease caused by an enveloped, single-stranded RNA virus belonging to the Morbillivirus genus of the Paramyxoviridae family. It typically presents [...] Read More
Healthcare-associated infections (HAIs) are common yet largely preventable through adherence to evidence-based guidelines. In 2005, Türkiye implemented a national infection control program, which led to significant reductions in HAI rates, including a 50% decrease in central line-associated bloodstream infections (CLABSIs) between 2008 and 2017. This result was in parallel with data from [...] Read More
Cervical cancer is the fourth most common cancer among women worldwide. Epidemiologically and molecularly, the human papillomavirus (HPV) is a circular, double-stranded DNA virus known to cause chronic infections and is the primary cause of cervical cancer. Other cancers associated with HPV include vulvar[...] Read More
Pityriasis rubra pilaris (PRP) is a papulosquamous disease of unknown etiology that progresses from keratoderma to erythroderma, particularly affecting the palms and soles. It is classified into five subtypes. The form associated with human immunodeficiency virus (HIV) infection is defined as type 6. Pityriasis rubra pilaris [...] Read More
Pantoea agglomerans, a Gram-negative, facultatively anaerobic bacterium in the Enterobacteriaceae family, was previously classified as Enterobacter agglomerans or Erwinia herbicola. Pantoea agglomerans is not an obligate pathogen for humans. However, two types of infections [...] Read More
