The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

Past Issue

December 2023, Volume 5, Issue 4


“Good” News from IDCM and Thanks to All Who Contributed

Murat Akova

The past year witnessed several big achievements for the IDCM which has become a half-a-decade old and a well-established scientific medium. The Journal has been indexed in the Web of Science Emerging Sources Citation Index (ESCI) since the very first issue in 2019. On the other hand, our statistics have substantially improved. Read More

Review Article

New Treatment Options in Chronic Hepatitis B: How Close Are We to Cure?

Pınar Korkmaz and others

Hepatitis B virus (HBV) infection is the leading cause of chronic liver disease worldwide. HBV-infected patients are at risk of developing liver cirrhosis and hepatocellular carcinoma (HCC) for life. Today, pegylated interferon (Peg-IFN) and nucleos(t)ide analogues (NAs) are used in the treatment of patients with chronic hepatitis B (CHB). Both treatment options have limitations. Read More

Is There a Role for Dark Field Microscopy in the Diagnosis of Lyme Disease?
A Narrative Review

Uğur Önal and others

Lyme disease, also known as Lyme borreliosis, is the most common vector-borne disease in Europe and North America, caused by the spirochete Borrelia species, which can be transmitted through the bite of an infected black-legged tick. The Centers for Disease Control and Prevention (CDC) data on Lyme disease in the United States showed (...) Read More

Original Article

Association of Serum Krebs von den Lungen-6 (KL-6) Levels and Disease Severity in Patients Hospitalized with COVID-19

Oğuz Evlice and others

Acute lung injury and sepsis are among the severe clinical outcomes of the coronavirus disease 2019 (COVID-19). Risk factors raise fatality rates, increase the burden on countries’ healthcare facilities, and significantly increase health expenditures due to prolonged inpatient periods. Several studies have revealed a severe illness course in COVID-19 patients, especially in males, older age, and comorbid (...) Read More

Bibliometric Analysis of Human Metapneumovirus Studies

Işıl Deniz Alıravcı and others

Human metapneumovirus (hMPV) is an enveloped, single-stranded ribonucleic acid (RNA) virus in the genus Metapneumovirus. In 2016, the Pneumoviridae family replaced Paramyxoviridae as a new classification for this virus. Read More

Evaluation of Hospitalized Patients with Community-Acquired Influenza-Like Illness During Two Influenza Seasons

Özge Özgen-Top and others

Influenza-like illness (ILI) can be caused by a range of respiratory viruses in adults. Influenza is one of the most important respiratory viruses that affects all age groups and can lead to hospitalizations. Severe influenza and complications can cause significant morbidity and mortality during pandemics, epidemics, and sporadic outbreaks. Therefore, influenza (...) Read More

How Successful Are APRI and FIB-4 Scores in Predicting Liver Fibrosis in Chronic Hepatitis B Patients?

Deniz Gür-Altunay and Pınar Yürük-Atasoy

Hepatitis B virus (HBV) infection is an important public health problem worldwide. It is the most important cause of acute and chronic liver disease and hepatocellular cancer. Hepatitis B infection is diagnosed by the detection of HBsAg in the serum or plasma. Chronic hepatitis B (CHB) infection is defined as the persistence of (...) Read More

Single-Dose Crossover Comparative Bioavailability Study of Two Different Posaconazole 100 mg Gastro-Resistant Tablets Under Fasted and Fed Conditions in Healthy Volunteers

Nilden Dayan and others

Posaconazole is a systemic extended-spectrum triazole mainly licensed for prophylaxis of invasive fungal infections (IFIs) in high-risk patients. Three formulations of posaconazole are currently available, including an oral suspension (40 mg/mL), a delayed-release gastric-resistant (...) Read More

Development of a Nanoplate-Based Digital PCR Test Method for Quantitative Detection of Human Adenovirus DNA

Yağmur Eylül Doğantürk and others

Human adenovirus (HAdV) is a non-enveloped, double-stranded DNA virus that causes self-limiting respiratory system infections, gastrointestinal tract infections, conjunctivitis, and meningitis. These infections are generally observed throughout the year with no seasonal distribution. Despite being self-limiting, HAdV infections (...) Read More

Brucellar Epididymo-Orchitis in a Brucellosis Hyperendemic Region in Türkiye

Hatun Öztürk-Çerik and others

Brucellosis is a widespread zoonosis transmitted to humans, mainly through direct or indirect contact with infected animals. The main endemic areas are the Mediterranean region, Middle East, Central Asia, China, India, sub-Saharan Africa, and Central and South America. Brucellosis is a systemic infection with a broad clinical spectrum (...) Read More

Psychosocial Status of Healthcare Workers During the COVID-19 Pandemic

Emrah Emiral and others

After the declaration of the pandemic on March 11, 2020, by the World Health Organization (WHO), approximately 771 million people were affected by COVID-19 globally, and about 7 million deaths have occurred as of the third week of November 2023. In Turkey, the first COVID-19 case was identified on March 11, 2020 (...) Read More

Case Report History of Infectious Diseases

Knidos Medical School and its Reflections on Modern Medicine

Önder Ergönül

Many people assumed that Asclepius was the God of Medicine and that her followers, the Asclepiads, were priests in temples and shrines called Asclepion. Asclepius and her daughter Hygeia who is known as goddess of hygiene are still the iconic names for modern medicine (Figure 1). However, as our knowledge deepened, it became possible to […] Read More

Acknowledgements to Reviewers


Murat Akova

The Editors sincerely thank to all reviewers of IDCM for their generous contribution to the Journal. The quality of the Journal depends on their valuable expertise. Read More