Review Article
Review Article
/ VOLUME 5, ISSUE 4, DECEMBER 2023
Pınar Korkmaz and others
Hepatitis B virus (HBV) infection is the leading cause of chronic liver disease worldwide. HBV-infected patients are at risk of developing liver cirrhosis and hepatocellular carcinoma (HCC) for life. Today, pegylated interferon (Peg-IFN) and nucleos(t)ide analogues (NAs) are used in the treatment of patients with chronic hepatitis B (CHB). Both treatment options have limitations. Read More
Review Article
/ VOLUME 5, ISSUE 4, DECEMBER 2023
Uğur Önal and others
Lyme disease, also known as Lyme borreliosis, is the most common vector-borne disease in Europe and North America, caused by the spirochete Borrelia species, which can be transmitted through the bite of an infected black-legged tick. The Centers for Disease Control and Prevention (CDC) data on Lyme disease in the United States showed (...) Read More
Review Article
/ VOLUME 5, ISSUE 3, SEPTEMBER 2023
Serap Şimşek-Yavuz
After the World Health Organization (WHO) declared an end to COVID-19 as a global public health emergency on May 5, 2023, we have entered a new era in the pandemic, and most countries have already returned to normal life. This declaration was resulted from the 12-month downward trend of the pandemic, increased immunity due to the highly effective vaccines, decreased death rates, and decreased pressure on once overwhelmed (...) Read More
Review Article
/ VOLUME 5, ISSUE 3, SEPTEMBER 2023
Merve Büyükkörük and others
The incidence of acute pancreatitis ranges from 2.2-136/100,000 people and increases by 3.7% per year. Necrosis occurs in nearly 15% of acute pancreatitis. The sterile necrosis of pancreatic or peripancreatic tissue gets infected by translocation of gastrointestinal flora or peripheral spread from the skin, respiratory, or urinary tract. Mortality rates increase with infection in necrotic tissue and rise from 19.8% to 35.2% in acute pancreatitis . Read More
Review Article
/ VOLUME 5, ISSUE 2, JUNE 2023
Uğur Önal and Halis Akalın
Patients with human immunodeficiency virus (HIV) infection or AIDS are more likely to have diseases that would not usually cause illness in a person with a healthy immune system, called opportunistic infections. Although significant efforts to improve progression along the HIV care continuum, (...) Read More
Review Article
/ VOLUME 4, ISSUE 4, DECEMBER 2022
Deniz Gökengin
It has been more than a decade since the first evidence of oral pre-exposure prophylaxis (PrEP) in the “Iniciativa Profilaxis Pre-Exposición” (iPreEx) study, which reported 44% efficacy. Following these results, the US Food and Drug Administration (FDA) approved PrEP in 2012 as a method of prevention from HIV for individuals at high risk, and two years later, the Centers for Disease Control and Prevention (CDC) published the PrEP guidelines. Then, many other (...) Read More
Review Article
/ VOLUME 2, ISSUE 2, AUGUST 2020
S.P. Bouopda Tamo
Each year, fungal infections affect more than one billion people worldwide, with more than 1.6 million deaths. Candidiasis accounts for 75 to 88% of these infections, and despite therapeutic advances, their incidence continues to increase with increasing mortality. The clinical spectrum of candidiasis extends from superficial diseases such as cutaneous, nail, digestive, and genital candidiasis, to systemic diseases such as candidemia. Read More
Review Article
/ VOLUME 2, ISSUE 1, APRIL 2020
İlker Kayı and Sibel Sakarya
In the statement he gave to the television program Nieuwsuuer on March 16, Sunday evening, the Head of Dutch National Institute for Public Health and the Environment (RIVM) Jaap van Dissel maintained that ‘an approach of total lockdown would lead the COVID-19 to bounce back’ and thereby they would employ the ‘maximum control’ strategy. Read More
Review Article
/ VOLUME 2, ISSUE 1, APRIL 2020
Gamze Özçürümez Bilgili
Disasters are large-scale events that are often unexpected and cause death, trauma, and destruction of property. Although there is no consistent definition of disasters in the literature, researchers generally agree that disasters share three key characteristics of large-scale traumatic events. First, disasters threaten to harm or death to a large group of people, Read More
Review Article
/ VOLUME 1, ISSUE 3, DECEMBER 2019
Abdullah Tarık Aslan and Murat Akova
Origins, characteristics and classification of extended-spectrum beta-lactamases (ESBLs) Currently, beta-lactamase family includes more than 2800 unique proteins. Although varied types of beta-lactamases have been specified to date, they have common topographic structures consisting of alpha-helices and beta-plated sheets. They most probably originated from environmental sources and produced against naturally occurring […] Read More
Review Article
/ VOLUME 1, ISSUE 3, DECEMBER 2019
Çağlayan Merve Ayaz and others
Actinomycosis, a chronic granulomatous condition, is caused by Actinomyces spp., a gram-positive anaerobic bacterium. Actinomyces spp. usually inhabit oral, gastrointestinal and female genital tract. The disease commonly manifests as slowly progressive cervicofacial (50% of cases), thoracic and pulmonary (15-20% ) or abdominopelvic (about 20% ) infection. Immunosuppression […] Read More
Review Article
/ VOLUME 1, ISSUE 3, DECEMBER 2019
Mahir Kapmaz and others
Infections of the yeasts other than Candida spp. are rare, but an emerging clinical entity. Clinicians should be alert for early diagnosis. Early distinction of non-Candida yeasts is important because of varying antifungal susceptibilities, higher mortality of 50-80% particularly among immunocompromised patients. These yeasts include Basidiomycetes […] Read More