COVID-19
Oğuz Evlice and others
The clinical spectrum of COVID-19 varies, ranging from asymptomatic infection to critical illness. The most commonly used tool for the classification of disease severity is the National Institute of Health (NIH) severity scale, which has four categories: mild, moderate, severe, and critical. Patients with moderate and severe clinical courses are followed up in wards, while those with (...) Read More
Yeşim Tuyji-Tok and others
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants have been detected since the summer of 2020, and their critical association with viral load, transmissibility, and escape from the innate-vaccine immune response were demonstrated. Another new variant was identified (...) Read More
İsmail Çelik and others
Since its emergence in December 2019, 530,266,292 confirmed coronavirus disease 2019 (COVID-19) cases, including 6,299,364 deaths were reported as of June 7, 2022. It’s widely accepted that in older age, comorbidities (hypertension, diabetes mellitus, obesity, chronic respiratory disease, (...) Read More
Vildan Avkan-Oğuz and others
Before coronavirus disease 2019 (COVID-19), antimicrobial stewardship (AMS) programs were essential for managing multidrug-resistant Gram-negative bacterial infections. In contrast, antifungal stewardship (AFS) programs were uncommon as a component of AMS. During the COVID-19 pandemic, both AMS and AFS programs have lost (...) Read More
Alara Altıntaş and others
COVID-19 has been the main focus of the world since the beginning of 2020. The virus has infected over 180 million people and caused about 6 million deaths worldwide up to February of 2022. With its rapid spread, the new coronavirus posed enormous economic, environmental, and social challenges together with health threats to the entire (...) Read More
İbrahim Toker and others
Coronavirus disease 2019 (COVID-19) occurred with different levels of severity, and different criteria for hospitalizations were suggested, considering risk factors for poor outcomes, such as advanced age, comorbidities, lymphopenia, and high C-reactive protein (CRP) levels. The most severe complication of COVID-19 is viral pneumonia, which is often manifested by diffuse bilateral lung (...) Read More
Mehmet Gökhan Gönenli and others
Healthcare workers were on the front line of the global effort against COVID-19. Thousands of physicians died from COVID-19 in many countries. In addition, difficulties in accessing personal protective equipment (PPE), lack of training, and workforce shortages have exposed the vulnerability of healthcare workers who desperately sought other options to protect (...) Read More
Hande Özportakal and others
The world has been fighting against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for more than two years, leading to more than 605 million cases and 6.4 million deaths as of September 11, 2022. Since the angiotensin-converting enzyme (ACE) is the functional receptor for SARS-CoV-2, predominantly expressed by the alveoli (...) Read More
Esma Eryılmaz-Eren and others
Coronavirus disease (COVID-19) has caused more than 660 million cases and more than six million deaths worldwide (1). COVID-19 can cause different clinical situations ranging from asymptomatic to life-threatening infections. Patients (...) Read More
Çaşıt Olgun Çelik and others
An acute respiratory syndrome (COVID-19), caused by a novel coronavirus (SARS-CoV-2), has spread from China worldwide and caused a pandemic that brought severe medical, social, and economic problems. The COVID-19 infection results in various clinical presentations ranging from an asymptomatic (...) Read More
Betül Çopur and others
COVID-19 is a fatal disease affecting all systems, especially the respiratory system. It manifests with different clinical characteristics, from asymptomatic infection to severe infection. Since its initial description, the disease has caused devastating effects and many deaths. Predictors of mortality (...) Read More
Murat Erdem and others
The standard method to detect SARS-CoV-2 has been real-time polymerase chain reaction (RT-PCR). Regardless of its high sensitivity and specificity, this method has some drawbacks as it requires complex and expensive equipment, extensive user training, (...) Read More
Özge Kaya and others
Psoriasis, a chronic inflammatory disease, has a multifactorial etiology, including genetic, environmental, and behavioral factors. Since psoriasis is an immune system-mediated disease, immunosuppressive agents and biological treatments are frequently used in its treatment; however, these agents are known to increase the risk of infection. This situation (...) Read More
Yeşim Yıldız and others
Vaccines to prevent SARS-CoV-2 infection are the most promising and effective approach to curb the COVID-19 pandemic, as well as to reduce hospitalizations and prevent mortality. In our country, the CoronaVac (Sinovac Biotech, China) vaccine started to be administered as of January 13, 2021, and the Comirnaty (BNT162b2, Pfizer-BioNTech) vaccine as (...) Read More
Reza Kamali Kakhki* and others
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory disease agent belonging to the Betacoronavirus genera. The genome of the virus translates into four major structural proteins, including spike (S), nucleocapsid (N), membrane (M), and envelop (E) proteins. During the pandemic, huge numbers of mutations (...) Read More
Mustafa Güldan and others
The coronavirus disease 2019 (COVID-19) caused more than 6 million deaths worldwide, and vaccination remains to be the most effective way to reduce the deaths in addition to infection control measures in the community. The Turkish Ministry of Health offered two types of vaccines (...) Read More
Uluhan Sili* and others
The first coronavirus disease 2019 (COVID-19) case in Turkey was reported on March 11, 2020. The number of confirmed cases with symptoms increased afterward, reaching 5000 per day by mid-April. With the effect of mitigation measures, the number of daily cases started to decline, (...) Read More
Zeynep Ece Kuloğlu and others
In the COVID-19 pandemic, it is essential to estimate the immune responses to various COVID-19 vaccinations to estimate the efficacy of the vaccines. During the ongoing pandemic, different vaccine types and vaccination strategies affect the cellular and molecular elements of innate and adaptive immune systems. Therefore, testing the effectiveness of COVID-19 vaccines in different vaccination (...) Read More
Nuriye Yalçın-Çolak and others
COVID-19, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is a zoonotic infection that emerged in Wuhan province of China in December 2019. SARS-COV-2 is a Betacoronavirus that is classified in Riboviria realm, Nidovirales order, and Coronaviridae family (1). Although the fatality rate of SARS-CoV-2 (2.6%) is lower than SARS-CoV (11%) and MERS-CoV (35-50%), it was much more severe worldwide (...) Read More
Serap Şimşek-Yavuz
After the World Health Organization (WHO) declared an end to COVID-19 as a global public health emergency on May 5, 2023, we have entered a new era in the pandemic, and most countries have already returned to normal life. This declaration was resulted from the 12-month downward trend of the pandemic, increased immunity due to the highly effective vaccines, decreased death rates, and decreased pressure on once overwhelmed (...) Read More