The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

Past Issue

December 2022, Volume 4, Issue 4


Infectious Diseases and Clinical Microbiology (IDCM): From Infancy to Maturity

Murat Akova

With this issue of the Journal, we are completing the fourth year of our publication life.  As of today, we can proudly say that IDCM has greatly improved considering every aspect of a successful scientific periodical. First, in order to respond to fast increasing submission rate, we changed our publishing frequency (...) Read More

Review Article

HIV Pre-Exposure Prophylaxis in Central and Eastern Europe-Gains and Challenges in An Ever-Changing World

Deniz Gökengin

It has been more than a decade since the first evidence of oral pre-exposure prophylaxis (PrEP) in the “Iniciativa Profilaxis Pre-Exposición” (iPreEx) study, which reported 44% efficacy. Following these results, the US Food and Drug Administration (FDA) approved PrEP in 2012 as a method of prevention from HIV for individuals at high risk, and two years later, the Centers for Disease Control and Prevention (CDC) published the PrEP guidelines. Then, many other (...) Read More

Original Article

Thyroid Dysfunction among the Patients with Critical COVID-19

Hande Özportakal and others

The world has been fighting against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for more than two years, leading to more than 605 million cases and 6.4 million deaths as of September 11, 2022. Since the angiotensin-converting enzyme (ACE) is the functional receptor for SARS-CoV-2, predominantly expressed by the alveoli (...) Read More

Analysis of the Prophylactic use of Hydroxychloroquine at the Beginning of the COVID-19 Pandemic Among Physicians

Mehmet Gökhan Gönenli and others

Healthcare workers were on the front line of the global effort against COVID-19. Thousands of physicians died from COVID-19 in many countries. In addition, difficulties in accessing personal protective equipment (PPE), lack of training, and workforce shortages have exposed the vulnerability of healthcare workers who desperately sought other options to protect (...) Read More

Comparison of CURB-65 Pneumonia Severity Score, Quick COVID-19 Severity Index, and Brescia-COVID Respiratory Severity Scale in Emergently Hospitalized COVID-19 Patients with Pneumonia

İbrahim Toker and others

Coronavirus disease 2019 (COVID-19) occurred with different levels of severity, and different criteria for hospitalizations were suggested, considering risk factors for poor outcomes, such as advanced age, comorbidities, lymphopenia, and high C-reactive protein (CRP) levels. The most severe complication of COVID-19 is viral pneumonia, which is often manifested by diffuse bilateral lung (...) Read More

Prevalence of Fosfomycin Resistance Among Enterobacterales Isolates in A Tertiary Care Hospital from Turkey

Yeliz Tanrıverdi-Çaycı and others

Urinary tract infections (UTIs) are seen in all age groups and are among the most frequent bacterial infections. Enterobacterales are the most common bacterial species that cause UTIs . Escherichia coli is the most common cause of both complicated UTIs (65%) and uncomplicated UTIs (75%). E. coli is followed by other Enterobacterales such as Klebsiella spp., Proteus spp., and Serratia spp. Resistance of urinary tract pathogens to (...) Read More

Stenotrophomonas maltophilia Bacteremia: From Diagnosis to Treatment

Pınar Aysert-Yıldız and others

Stenotrophomonas maltophilia is an aerobic, non-fermentative, Gram-negative bacterium widespread in aquatic environments and soil. It has an inherent ability to adhere to abiotic surfaces and forms biofilms. It is usually considered to be a commensal and a low-grade pathogen. However, it can cause severe infections in the immunocompromised and debilitated (...) Read More

Prospective Evaluation of Infections in Geriatric Patients in Intensive Care Units

Hasan Naz and others

Nosocomial infections (NIs) constitute a major health issue in terms of morbidity, high mortality, prolonged hospitalization, and increased costs of direct patient care. While beds in intensive care units (ICUs) constitute less than 10% of all hospital beds, more than 20% of all NIs develop in the ICU. The human lifespan has been prolonged (...) Read More

Evaluation of Blood Stream and Biliary Tract Infections Related to Percutaneous Transhepatic Cholangiography and Prophylaxis Given in Patients with Malignancy

Halime Araz and others

Percutaneous transhepatic cholangiography (PTC) is an invasive procedure used in patients with obstructive jaundice in the progress of some malignancies to reduce bilirubin levels, improve liver functions, prolong survival and enable other treatments. The procedure is critical because of its potential complications. The most common (...) Read More

Case Report

Recurrent Nocardial Brain Abscess Developing in an Immunocompetent Patient, A Case Report

Suzan Şahin and Şirin Menekşe

Central nervous system nocardiosis is rare but has high morbidity and mortality. Nocardia is found in soil, decomposing vegetation, and other organic matter, as well as in water as saprophytes. The infection usually occurs through direct inoculation of the microorganism from a skin injury or via inhalation.  The pulmonary form (...) Read More

A Rare Presentation of Leptospirosis: Dysarthria and Guillain-Barré Syndrome

Özlem Akdoğan and others

Leptospirosis is one of the zoonotic infections seen in Turkey. Most cases demonstrate a mild clinical course, and the disease is self-limiting. Complaints such as fever, headache, myalgia, nausea, and vomiting are the most common reasons for presentation. Severe cases can have polymyositis, liver involvement, icterus and (...) Read More

Fasciola hepatica in the Differential Diagnosis of a Patient with Obstructive Jaundice and Eosinophilia

Necati Mumcu and others

Although Fasciola hepatica infects sheep and cattle, it can sometimes be an accidental host in humans. Clinically, fever, abdominal pain, intermittent jaundice, intrahepatic cystic abscess, eosinophilic cholecystitis, and extrahepatic cholecystitis are seen most frequently. The diagnosis can be made by serology or by clinical improvement (...) Read More

A Case of Clostridioides difficile Infection of a Pregnant Woman Treated with Colectomy

Süda Tekin and others

Clostridioides difficile infections (CDIs) can present in various clinical forms, ranging from an asymptomatic carrier state to pseudomembranous colitis (PMC), and are recognized as one of the leading causes of diarrhea in healthcare centers. C. difficile-associated PMC is a life-threatening inflammatory bowel disease and may result in (...) Read More

In Memoriam Acknowledgements to Reviewers


Murat Akova

The Editors sincerely thank to all reviewers of IDCM for their generous contribution to the Journal. The quality of the Journal depends on their valuable expertise. Ahmet Çağkan İnkaya, Ankara, Turkey Alpay Azap, Ankara, Turkey Alper Tekeli, Ankara, Turkey Ayca Arzu Sayıner, […] Read More