The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)
In recent decades, fungal infections of the central nervous system (CNS) have increased significantly. Of more than 100,000 identified fungal species, approximately 10 to 15% are responsible for implicated fungal-related neurological diseases. A significant clinical manifestation of fungal infections of the CNS is meningitis, a serious condition marked [...] Read More
Antibiotic resistance has become a significant public health concern, primarily due to irrational antibiotic use. Healthcare and antimicrobial stewardship depend on using antibiotics correctly for several reasons. In the first place, adhering to the prescribed dosage ensures that the body receives the right amount of antibiotics to treat [...] Read More
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), led to significant hospitalizations and mortality globally from 2019 to 2021. According to data from the World Health Organization (WHO), over 776 million COVID-19 cases and more than 7 million COVID-19-related deaths have been reported to date. Although [...] Read More
Coronavirus disease 2019 (COVID-19) is a disease with a wide clinical spectrum ranging from mild to moderate illness to acute respiratory distress syndrome (ARDS) and death. Approximately 25% of patients with COVID-19-related ARDS required mechanical ventilation due to respiratory failure and were treated in intensive [...] Read More
The straightforward way to keep the course of the pandemic under control is herd immunity, which is established with a vaccine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). There is a need to develop appropriate laboratory tools to predict the efficacy of vaccines and evaluate the post-vaccination immune response. Read More
Group B Streptococcus (GBS), Streptococcus agalactiae, is generally found as a colonizer of the genital and gastrointestinal tracts, and vertical transmission from colonized mothers to newborns during childbirth can result in serious infections. This bacterium is a leading cause of sepsis and meningitis in neonates and is also associated with several invasive and non-invasive [...] Read More
Cytomegalovirus (CMV) is a DNA belonging to the family Herpesviridae and subfamily Betaherpesvirinae. CMV seropositivity rate in Turkiye varies between 85% and 100% . Following primary infection, CMV remains latent for life in myeloid cells, such as monocytes, macrophages, and dendritic cells. It can reactivate when [...] Read More
Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, typically presents with mild to moderate course in the majority of infected individuals. During the pandemic, nearly 30% of patients required hospitalization, and a subset developed a severe disease characterized by respiratory failure and needed intensive care support. Read More
Healthcare-associated infections are frequently encountered in intensive care units (ICUs), with more than 30% of all ICU admissions having an infection. For decades, antibiotics have provided an effective treatment for infectious diseases. Since most antibiotic resistance is caused by misuse or abuse of antibiotics, one of the strategies that could [...] Read More
Parvovirus B19 (PVB19) is a single-stranded DNA virus belonging to the family Parvoviridae. It can cause erythema infectiosum, arthropathies, aplastic crisis, immune-mediated rash, and arthritis. Dermatological manifestations of acute PVB19 infection include vesiculopustular rash, petechiae, purpura, glove sock syndrome [...] Read More
Leishmaniasis is a vector-borne parasitic disease transmitted by the bite of infected female sandflies. Leishmania species can cause various clinical manifestations, ranging in severity from spontaneously regressing cutaneous lesions to visceral disease, which is fatal in over 95% of cases if left untreated. Visceral leishmaniasis (VL) presents unexplained [...] Read More
Chronic lymphocytic leukemia (CLL) is characterized by the clonal proliferation of mature-appearing neoplastic B lymphocytes in lymphoid tissues, including peripheral blood, bone marrow, lymph nodes, spleen, and liver. Hypogammaglobulinemia, along with functional impairments in T cells and certain subgroups [...] Read More
Anthrax is an acute zoonotic disease caused by the Gram-positive bacillus Bacillus anthracis, which primarily affects herbivores. It manifests as cutaneous, gastrointestinal, or respiratory anthrax, depending on the route by which the bacteria enter the body. Cutaneous anthrax often occurs during the handling of infected animals while the gastrointestinal and pulmonary forms result from consuming contaminated [...] Read More
In the 19th century, childbed fever claimed the lives of many women following childbirth. At the Vienna General Hospital (Allgemeines Krankenhaus der Stadt Wien), there were two obstetrics clinics: one staffed by physicians and medical students, and the other exclusively by [...] Read More
