Original Article
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
Melike İnan-Hekimoğlu and others
Cytomegalovirus (CMV) is a DNA virus from the Herpesviridae family that can remain latent in the body for life after primary infection and reactivate and cause viral shedding, especially in cases of immunosuppression. In studies conducted in different patient groups from Türkiye, CMV seroprevalence was reported to be between 85-100%. CMV can affect […] Read More
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
Oruç Numan Gökçe and others
Cystic echinococcosis (CE), caused mainly by Echinococcus granulosus, is a parasitic disease common in Mediterranean countries such as Türkiye. Although it can occur anywhere in the body, it predominantly affects the liver. The disease is often asymptomatic; thus, cysts are often detected incidentally during imaging studies performed for other purposes. Read More
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
Muhammet Çağrı Yıldız and others
Real-time reverse transcriptase polymerase chain reaction (RT-PCR) is widely used to diagnose SARS-CoV-2. However, PCR tests need expensive equipment and qualified personnel, which makes them only used in high throughput and advanced laboratory settings. Improvements in SARS-CoV-2 diagnosis with easy, rapid, and cost-effective approaches […] Read More
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
Khalis Mustafayev and others
Invasive Candida infections have increased significantly in recent years due to various risk factors, including invasive procedures, vascular catheterization, intra-abdominal surgery, prolonged use of broad-spectrum antibiotics, immunosuppressive medications, hemodialysis, total parenteral nutrition (TPN), and extended intensive care unit (ICU) stays. Candida, one of the top three nosocomial bloodstream infections, [...] Read More
Original Article
/ VOLUME 6, ISSUE 4, DECEMBER 2024
Dilara Yıldırım and others
Tuberculosis (TB) is a common disease with high mortality and morbidity worldwide. Globally, an estimated 10.6 million people (95% uncertainty interval [UI]=9.9-11.4 million) developed TB in 2022, compared with 10.3 million in 2021 and 10.0 million in 2020. TB caused an estimated 1.30 million deaths worldwide in 2022 (95% UI=1.18-1.43 million). This was […] Read More
Original Article
/ VOLUME 6, ISSUE 3, SEPTEMBER 2024
Süreyya Damar-Örenler and others
Human immunodeficiency virus (HIV) remains a significant global health challenge with societal impacts. Despite a decline in the annual number of new cases worldwide, the incidence of HIV is on the rise in the Eastern Europe/Central Asia region, including Türkiye. With the introduction of new antiretroviral treatments (ARTs), HIV has transitioned from a […] Read More
Original Article
/ VOLUME 6, ISSUE 3, SEPTEMBER 2024
Zeynep Bilgiç and others
The use of antiretroviral therapy (ART) in individuals with the human immunodeficiency virus (HIV) has significantly increased their life expectancy. Nevertheless, an increase in the frequency of chronic diseases such as diabetes mellitus (DM), hypertension (HT), and cardiovascular disease (CVD) in this population with advancing age is expected. Also, they are at greater […] Read More
Original Article
/ VOLUME 6, ISSUE 3, SEPTEMBER 2024
Kauke Bakari Zimbwe and others
Antimicrobial resistance (AMR) is declared one of humanity’s top ten global public health threats. AMR is associated with increased hospitalizations, extended hospital stays, readmissions, and a higher mortality risk. In 2019, 4.95 million deaths, including 1.27 million directly attributable, were associated with bacterial AMR. Sub-Saharan Africa has the highest all-age death rate [...] Read More
Original Article
/ VOLUME 6, ISSUE 3, SEPTEMBER 2024
Kadir Görkem Güçlü and others
Hepatitis B virus (HBV) infection remains a significant public health issue globally. According to the latest data released by the World Health Organization (WHO) in July 2023, the number of individuals living with chronic hepatitis B (CHB) infection as of 2019 was reported as 296 million, with 820 million deaths attributed to cirrhosis and hepatocellular carcinoma [...] Read More
Original Article
/ VOLUME 6, ISSUE 3, SEPTEMBER 2024
Okan Derin
Hepatitis B is an important global infectious disease. With its high prevalence and serious complications, such as liver cirrhosis, hepatocellular cancer, and death, controlling and monitoring hepatitis B is of paramount importance. In this context, the Global Burden of Disease (GBD) study dataset is an important resource for analyzing the prevalence[...] Read More
Original Article
/ VOLUME 6, ISSUE 3, SEPTEMBER 2024
Hasan Selçuk Özger and others
Procalcitonin (PCT) is a biomarker frequently used in the diagnosis and prognosis of infection. The lack of optimum cut-off values and the high serum PCT levels in some non-infectious conditions restrict its clinical use. Therefore, PCT use is not recommended regardless of clinical parameters. This limitation in clinical use has led to PCT kinetic evaluations rather than predictions [...] Read More
Original Article
/ VOLUME 6, ISSUE 3, SEPTEMBER 2024
Yunus Gürbüz and others
In 75-85% of cases of acute hepatitis C infection, the disease becomes chronic and carries a risk of developing liver failure and hepatocellular cancer. In its global hepatitis report published in 2017, the World Health Organization (WHO) reported that 71.1 (95% uncertainty interval [UI]: 62.1-79.0 million) million people were chronically infected with the hepatitis C virus [...] Read More
Original Article
/ VOLUME 6, ISSUE 3, SEPTEMBER 2024
Pınar Korkmaz and others
Coronavirus disease (COVID-19) remarkably impacted mortality rates and healthcare resources. The causative virus, SARS-CoV-2, is a member of the β family. Pulmonary manifestations of COVID-19 can range from asymptomatic infection to severe pneumonia and acute respiratory distress syndrome. Research regarding risk classifications [...] Read More
Original Article
/ VOLUME 6, ISSUE 2, JUNE 2024
Muhammed Fatih Karaşın and others
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a strain of the coronavirus that causes COVID-19, spread rapidly around the world and was defined as a pandemic on March 12, 2020, by the World Health Organization. As of June 2023, more than 767 million cases were confirmed globally, along with 6.9 million deaths. Read More
Original Article
/ VOLUME 6, ISSUE 2, JUNE 2024
Bahar Madran and others
The global impact of the coronavirus disease (COVID-19) pandemic has been profound, affecting billions of lives worldwide. As of June 13, 2024, the virus has infected approximately 704 million people and led to a staggering death toll of 7 million. In the fight against this devastating virus, the development and distribution of COVID-19 vaccines have been identified (...) Read More
Original Article
/ VOLUME 6, ISSUE 2, JUNE 2024
Zeynep Tekin-Taş and others
Hip and knee arthroplasties stand out as the most prevalent surgical interventions employed to address joint deformities, predominantly stemming from osteoarthritis associated with an aging population. In Turkey, a total of 34,240 hip arthroplasties and 81,109 knee arthroplasties were conducted in 2022. Meanwhile, in the United States of America (...) Read More
Original Article
/ VOLUME 6, ISSUE 2, JUNE 2024
Elif M. Sarıcaoğlu and Fügen Yörük
Staphylococcus aureus, particularly methicillin-resistant Staphylococcus aureus (MRSA), is a major cause of serious hospital and community-acquired infections and is associated with increased health care costs, prolonged antibiotic treatment and hospitalization, morbidity, and mortality. While glycopeptides (...) Read More
Original Article
/ VOLUME 6, ISSUE 2, JUNE 2024
Rüveyda Korkmazer and others
Urinary tract infection (UTI) affects approximately 150 million people worldwide every year and is encountered in all age groups. Escherichia coli, Klebsiella spp., group B streptococcus, and Enterococcus spp. are the most frequent species. The increase in antibiotic resistance rates among these agents leads to failures in empirical treatment and causes an increase in mortality, morbidity rates, and costs. Read More
Original Article
/ VOLUME 6, ISSUE 2, JUNE 2024
Mervenur Demir and others
The global increase in the rate of multi-drug resistant (MDR) bacterial infections in recent years is an important public health problem that limits the therapeutic options. The issue becomes particularly critical in cases of bloodstream infections (BSI) in which delay is associated with high mortality rates. Bacteria grown in blood cultures (BC) must be subcultured on the solid media (...) Read More
Original Article
/ VOLUME 6, ISSUE 2, JUNE 2024
Merve Arslan and others
Infective endocarditis is a clinical condition that affects the endocardial surface of the heart, involving natural or prosthetic heart valves and intracardiac devices. It is a high-cost and high-mortality infectious disease with an increasing incidence and is more frequently diagnosed with advancing diagnostic methods. Along with well-defined cardiac (previous endocarditis, presence of intracardiac prosthetic materials, (...) Read More