The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

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Editorial

“Good” News from IDCM and Thanks to All Who Contributed

Murat Akova

The past year witnessed several big achievements for the IDCM which has become a half-a-decade old and a well-established scientific medium. The Journal has been indexed in the Web of Science Emerging Sources Citation Index (ESCI) since the very first issue in 2019. On the other hand, our statistics have substantially improved. Read More

Original Article

Association of Serum Krebs von den Lungen-6 (KL-6) Levels and Disease Severity in Patients Hospitalized with COVID-19

Oğuz Evlice and others

Acute lung injury and sepsis are among the severe clinical outcomes of the coronavirus disease 2019 (COVID-19). Risk factors raise fatality rates, increase the burden on countries’ healthcare facilities, and significantly increase health expenditures due to prolonged inpatient periods. Several studies have revealed a severe illness course in COVID-19 patients, especially in males, older age, and comorbid (...) Read More

How Successful Are APRI and FIB-4 Scores in Predicting Liver Fibrosis in Chronic Hepatitis B Patients?
Original Article

How Successful Are APRI and FIB-4 Scores in Predicting Liver Fibrosis in Chronic Hepatitis B Patients?

Deniz Gür-Altunay and Pınar Yürük-Atasoy

Hepatitis B virus (HBV) infection is an important public health problem worldwide. It is the most important cause of acute and chronic liver disease and hepatocellular cancer. Hepatitis B infection is diagnosed by the detection of HBsAg in the serum or plasma. Chronic hepatitis B (CHB) infection is defined as the persistence of (...) Read More

Early Release - Original Article

How Reliable is ChatGPT as a Novel Consultant in Infectious Diseases and Clinical Microbiology?

Gülşah Tunçer and Kadir Görkem Güçlü

Artificial intelligence models have influenced many branches of science in recent years. It is used in various departments of medicine. ChatGPT (Chat Generative Pre-trained Transformer) is a text-based artificial intelligence model developed by OpenAI. ChatGPT can be used in many areas of medicine, such as to generate medical text, answer medical questions, provide recommendations for diagnosis and treatment (...) Read More

Single-Dose Crossover Comparative Bioavailability Study of Two Different Posaconazole 100 mg Gastro-Resistant Tablets Under Fasted and Fed Conditions in Healthy Volunteers
Original Article

Single-Dose Crossover Comparative Bioavailability Study of Two Different Posaconazole 100 mg Gastro-Resistant Tablets Under Fasted and Fed Conditions in Healthy Volunteers

Nilden Dayan and others

Posaconazole is a systemic extended-spectrum triazole mainly licensed for prophylaxis of invasive fungal infections (IFIs) in high-risk patients. Three formulations of posaconazole are currently available, including an oral suspension (40 mg/mL), a delayed-release gastric-resistant (...) Read More

Development of a Nanoplate-Based Digital PCR Test Method for Quantitative Detection of Human Adenovirus DNA
Original Article

Development of a Nanoplate-Based Digital PCR Test Method for Quantitative Detection of Human Adenovirus DNA

Yağmur Eylül Doğantürk and others

Human adenovirus (HAdV) is a non-enveloped, double-stranded DNA virus that causes self-limiting respiratory system infections, gastrointestinal tract infections, conjunctivitis, and meningitis. These infections are generally observed throughout the year with no seasonal distribution. Despite being self-limiting, HAdV infections (...) Read More

Review Article

New Treatment Options in Chronic Hepatitis B: How Close Are We to Cure?

Pınar Korkmaz and others

Hepatitis B virus (HBV) infection is the leading cause of chronic liver disease worldwide. HBV-infected patients are at risk of developing liver cirrhosis and hepatocellular carcinoma (HCC) for life. Today, pegylated interferon (Peg-IFN) and nucleos(t)ide analogues (NAs) are used in the treatment of patients with chronic hepatitis B (CHB). Both treatment options have limitations. Read More

Review Article

Is There a Role for Dark Field Microscopy in the Diagnosis of Lyme Disease?
A Narrative Review

Uğur Önal and others

Lyme disease, also known as Lyme borreliosis, is the most common vector-borne disease in Europe and North America, caused by the spirochete Borrelia species, which can be transmitted through the bite of an infected black-legged tick. The Centers for Disease Control and Prevention (CDC) data on Lyme disease in the United States showed (...) Read More

Original Article

Evaluation of Hospitalized Patients with Community-Acquired Influenza-Like Illness During Two Influenza Seasons

Özge Özgen-Top and others

Influenza-like illness (ILI) can be caused by a range of respiratory viruses in adults. Influenza is one of the most important respiratory viruses that affects all age groups and can lead to hospitalizations. Severe influenza and complications can cause significant morbidity and mortality during pandemics, epidemics, and sporadic outbreaks. Therefore, influenza (...) Read More