The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)
Peritonitis presents an inflammation of the peritoneal cavity that can develop because of infectious (bacteria, viruses, parasites, etc.) and non-infectious (chemical agents, foreign substances, etc.) causes. Infectious peritonitis is divided into three classes based on [...] Read More
Antimicrobial resistance (AMR) is declared one of humanity’s top ten global public health threats. AMR is associated with increased hospitalizations, extended hospital stays, readmissions, and a higher mortality risk. In 2019, 4.95 million deaths, including 1.27 million directly attributable, were associated with bacterial AMR. Sub-Saharan Africa has the highest all-age death rate [...] Read More
Staphylococcus aureus, particularly methicillin-resistant Staphylococcus aureus (MRSA), is a major cause of serious hospital and community-acquired infections and is associated with increased health care costs, prolonged antibiotic treatment and hospitalization, morbidity, and mortality. While glycopeptides (...) Read More
Urinary tract infection (UTI) affects approximately 150 million people worldwide every year and is encountered in all age groups. Escherichia coli, Klebsiella spp., group B streptococcus, and Enterococcus spp. are the most frequent species. The increase in antibiotic resistance rates among these agents leads to failures in empirical treatment and causes an increase in mortality, morbidity rates, and costs. Read More
The global increase in the rate of multi-drug resistant (MDR) bacterial infections in recent years is an important public health problem that limits the therapeutic options. The issue becomes particularly critical in cases of bloodstream infections (BSI) in which delay is associated with high mortality rates. Bacteria grown in blood cultures (BC) must be subcultured on the solid media (...) Read More
Healthcare-associated infections (HAI) is an increasing global problem all over the world. Multidrug-resistant (MDR) pathogens, including carbapenem-resistant Gram-negative Enterobacterales, Pseudomonas spp. and Acinetobacter spp. have become common causes of HAI, such as central line-associated bloodstream infections (BSIs), catheter-associated urinary tract infections (UTIs), surgical site infections (SSIs) and ventilatory associated pneumonia (VAPs). These infections increase not only mortality but also healthcare Read More
Surgical site infections (SSI) are defined as infections that occur up to 30 days or one year after surgery in patients with implants, affecting the incision or deep tissue at the surgery site. They account for 20% of all healthcare-associated infections (HAI) in hospitalized patients. Patients with SSI are hospitalised additionally 7-11 days postoperatively. Read More
Complicated intra-abdominal infection (cIAI) is defined as localized or diffuse peritonitis with the involvement of multiple intraperitoneal organs. Source control and appropriate empirical antibiotics are essentials of the treatment. There are few clinical and microbiologic studies regarding cIAI in Turkey. Empiric antibiotics were selected due to diagnoses; community-acquired IAI (CA-IAI) or healthcare-associated IAI. Guidelines published on this topic lack definitive criteria for CA-IAI. Read More
Acinetobacter baumannii is one of the most pathogenic nosocomial infection agents because of its extreme resistance to almost all known antibiotics and host immune responses . The emergence of colistin-resistance in A. baumannii has been reported throughout the world. Read More