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December 2019, Volume 1, Issue 3

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Editorial

Reviewers-2019

Murat Akova

The Editors sincerely thank to all reviewers of IDCM for their generous contribution to the Journal. The quality of the Journal depends on their valuable expertise. […] Read More

IDCM Newsfeed

Almost 40 Years into the HIV Epidemic: Are We Turning the Tide?

Ayşe Deniz Gökengin

Over the past 38 years following the introduction of HIV infection, which affected the lives of 75 million people, many scientific advances in prevention, diagnosis, treatment and care have been recorded, and the lives of people living with HIV (PLWH) have been transformed. Currently, life expectancy for PLWH who are diagnosed early and who initiate [...] Read More

Original Article

Rapid Detection of Difficult-to-Culture Bacterial Pathogens Using Real-time Nanopore Sequencing

Aycan Gündoğdu and others

Infectious diseases are the leading causes of mortality and morbidity worldwide. Current diagnosis of clinically significant infectious agents is based on a variety of laboratory-based tests including microscopy, culture, immunoassays and nucleic acid amplification. The majority of these techniques relies on conventional culture-based profiling […] Read More

Public Knowledge and Attitudes Regarding Antibiotic Use in Ankara, Turkey

Alpay Azap and others

The discovery of antibiotics has been a milestone for the treatment of infectious diseases. However, soon after antimicrobials came into use, it has been recognized that microorganisms become resistant. Antimicrobial resistance decreases the number of treatment options available in infectious diseases. Currently, antimicrobial resistance has become an issue […] Read More

Case Report

A Severe Sight-threatening Complication of Herpes Zoster Ophthalmicus: Orbital Apex Syndrome

Sumru Onal and others

Varicella-zoster virus (VZV) is found in worldwide distribution and can lead to two distinct viral syndromes. Primary infection occurs as varicella and is a contagious and usually benign childhood disease. Herpes zoster (HZ) presents as unilateral pain in a dermatomal distribution accompanied by a vesicular rash. Herpes zoster generally occurs in older adults and results from the reactivation of latent VZV […] Read More

Review Article

Infections Caused by Extended-Spectrum β-lactamase-Producing Enterobacteriaceae: Clinical and Molecular Epidemiology and Treatment Strategies

Abdullah Tarık Aslan and Murat Akova

Origins, characteristics and classification of extended-spectrum beta-lactamases (ESBLs) Currently, beta-lactamase family includes more than 2800 unique proteins. Although varied types of beta-lactamases have been specified to date, they have common topographic structures consisting of alpha-helices and beta-plated sheets. They most probably originated from environmental sources and produced against naturally occurring […] Read More

Splenic Actinomycosis in a Patient with Chronic Granulomatous Disease: A Case Report and Review of the Literature

Çağlayan Merve Ayaz and others

Actinomycosis, a chronic granulomatous condition, is caused by Actinomyces spp., a gram-positive anaerobic bacterium. Actinomyces spp. usually inhabit oral, gastrointestinal and female genital tract. The disease commonly manifests as slowly progressive cervicofacial (50% of cases), thoracic and pulmonary (15-20% ) or abdominopelvic (about 20% ) infection. Immunosuppression […] Read More

Rare Yeasts: Emerging Threat in Immunocompromised Patients

Mahir Kapmaz and others

Infections of the yeasts other than Candida spp. are rare, but an emerging clinical entity. Clinicians should be alert for early diagnosis. Early distinction of non-Candida yeasts is important because of varying antifungal susceptibilities, higher mortality of 50-80% particularly among immunocompromised patients. These yeasts include Basidiomycetes […] Read More