The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

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Original Article / VOLUME 7, ISSUE 2, JUNE 2025

Detection of Hypervirulent ST-17 Clone Among Clinical Group B Streptococcus Isolates Using MALDI-TOF MS and PCR

Gülşah Malkoçoğlu and others

Group B Streptococcus (GBS), Streptococcus agalactiae, is generally found as a colonizer of the genital and gastrointestinal tracts, and vertical transmission from colonized mothers to newborns during childbirth can result in serious infections. This bacterium is a leading cause of sepsis and meningitis in neonates and is also associated with several invasive and non-invasive [...] Read More

Original Article / VOLUME 7, ISSUE 2, JUNE 2025

Quantitative Immunoglobulin G and Interferon-Gamma Responses After Different Booster Strategies of CoronaVac and BNT162b2 Vaccines in Türkiye

Aylin İrem Ocaklı and others

The straightforward way to keep the course of the pandemic under control is herd immunity, which is established with a vaccine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). There is a need to develop appropriate laboratory tools to predict the efficacy of vaccines and evaluate the post-vaccination immune response. Read More

Original Article / VOLUME 7, ISSUE 2, JUNE 2025

Prognostic Factors in COVID-19 Patients with Ventilator-Associated Pneumonia: A Single-Centre Experience

Hilal Ekici and others

Coronavirus disease 2019 (COVID-19) is a disease with a wide clinical spectrum ranging from mild to moderate illness to acute respiratory distress syndrome (ARDS) and death. Approximately 25% of patients with COVID-19-related ARDS required mechanical ventilation due to respiratory failure and were treated in intensive [...] Read More

Original Article / VOLUME 7, ISSUE 2, JUNE 2025

The Role of Serial Monitoring of Laboratory Parameters in Determining the Need for Intensive Care in Severe COVID-19: A Single-Center Retrospective Study

Elif Nur Özbay-Haliloğlu and Zeynep Tekin-Taş

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), led to significant hospitalizations and mortality globally from 2019 to 2021. According to data from the World Health Organization (WHO), over 776 million COVID-19 cases and more than 7 million COVID-19-related deaths have been reported to date. Although [...] Read More

Original Article / VOLUME 7, ISSUE 2, JUNE 2025

The Definition, Prevalence, and Risk Factors of Augmented Renal Clearance in Adult Patients on Antimicrobial Therapy: A Scoping Review

Hasan Memiş and others

Antibiotic resistance has become a significant public health concern, primarily due to irrational antibiotic use. Healthcare and antimicrobial stewardship depend on using antibiotics correctly for several reasons. In the first place, adhering to the prescribed dosage ensures that the body receives the right amount of antibiotics to treat [...] Read More

Original Article / VOLUME 7, ISSUE 2, JUNE 2025

Characteristics and Distribution of Fungal Meningitis: A Systematic Review

Armina Khalilzadegan and others

In recent decades, fungal infections of the central nervous system (CNS) have increased significantly. Of more than 100,000 identified fungal species, approximately 10 to 15% are responsible for implicated fungal-related neurological diseases. A significant clinical manifestation of fungal infections of the CNS is meningitis, a serious condition marked [...] Read More